Anti-LPL antibodies are used in the immunodetection of the protein lipoprotein lipase. In humans, the canonical protein has a reported length of 475 amino acid residues and a mass of 53.2 kDa. Its subcellular localization is in the extracellular matrix, cell membrane, and is secreted. It is notably expressed in blood plasma. A member of the Lipase protein family, LPL is known to be a key enzyme in triglyceride metabolism. Post-translational modifications have been described, including glycosylation. The LPL gene has been associated with the disease, Hyperlipoproteinemia. Synonyms for this target antigen include LIPD, phospholipase A1, and HDLCQ11. LPL gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Over 80 citations in the literature describe the use of LPL antibodies in research. Western Blot is a widely used application for these antibodies. Immunofluorescence and Immunohistochemistry are also common applications.