Anti-GTF2H4 antibodies are used in the immunodetection of the protein general transcription factor IIH subunit 4. In humans, the canonical protein has a reported length of 462 amino acid residues and a mass of 52.2 kDa. Its subcellular localization is in the nucleus. Up to 2 different isoforms have been reported for this protein. A member of the TFB2 protein family, GTF2H4 is a known component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. Synonyms for this target antigen include TFB2, TFIIH, BTF2 p52, TFIIH basal transcription factor complex p52 subunit, and P52. GTF2H4 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Western Blot is a widely used application for the GTF2H4 antibodies listed below. In addition, ELISA is also a common application.