Anti-SEMA3A antibodies are used in the immunodetection of the protein semaphorin 3A. In humans, the canonical protein has a reported length of 771 amino acid residues and a mass of 88.9 kDa. It has been described to be a secreted protein. It is reported to be expressed in the dorsal root ganglia. A member of the Semaphorin protein family, SEMA3A is reported to be involved in development of the olfactory system and in neuronal control of puberty. Post-translational modifications have been described, including glycosylation.
The SEMA3A marker can be used to identify Gray Matter MGE Interneurons.* Synonyms for this target antigen include HH16, Hsema-I, Hsema-III, SEMA1, SEMAD, SEMAIII, SEMAL, and COLL1. SEMA3A gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. A number of SEMA3A antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.
*HuBMAP Human Reference Atlas v1.4