Anti-SETD4 antibodies are used in the immunodetection of the protein SET domain containing 4. In humans, the canonical protein has a reported length of 440 amino acid residues and a mass of 50.4 kDa. Its subcellular localization is in the nucleus and cytoplasm. Up to 4 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. A member of the SETD4 protein family, SETD4 is reported to be a Histone-lysine N-methyltransferase that acts as a regulator of cell proliferation, cell differentiation and inflammatory response. Synonyms for this target antigen include C21orf27, SET domain-containing protein 4, and C21orf18. SETD4 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some SETD4 antibodies may have been used in research and have associated citations. These antibodies are most commonly used in Western Blot experiments, among other applications.