Anti-RMND5B antibodies are used in the immunodetection of the protein required for meiotic nuclear division 5 homolog B. In humans, the canonical protein has a reported length of 393 amino acid residues and a mass of 44.4 kDa. Its subcellular localization is in the cytoplasm. Up to 2 different isoforms have been reported for this protein. RMND5B is an important component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. Synonyms for this target antigen include GID complex subunit 2 homolog B, protein RMD5 homolog B, and E3 ubiquitin-protein transferase RMND5B. RMND5B gene orthologs have been reported in the mouse, rat, bovine, zebrafish and chimpanzee species. Immunohistochemistry is the most common application for the Rmnd5b antibodies listed below. ELISA, Western Blot, and Immunofluorescence are also common applications.