Anti-HDDC2 antibodies are used in the immunodetection of the protein HD domain containing 2. In humans, the canonical protein has a reported length of 204 amino acid residues and a mass of 23.4 kDa. Up to 3 different isoforms have been reported for this protein. It is notably expressed in many tissues, such as the bronchus, tonsil, and adrenal gland. A member of the HDDC2 protein family, HDDC2 is known to catalyze the dephosphorylation of the nucleoside 5'-monophosphates deoxyadenosine monophosphate (dAMP), deoxycytidine monophosphate (dCMP), deoxyguanosine monophosphate (dGMP) and deoxythymidine monophosphate (dTMP). Synonyms for this target antigen include CGI-130, NS5ATP2, dJ167O5.2, 5'-deoxynucleotidase HDDC2, HCV NS5A-transactivated protein 2, and C6orf74. HDDC2 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Immunohistochemistry is the most common application for the HDDC2 antibodies listed below. Western Blot and Immunofluorescence are also common applications.