Anti-IRF6 antibodies are used in the immunodetection of the protein interferon regulatory factor 6. In humans, the canonical protein has a reported length of 467 amino acid residues and a mass of 53.1 kDa. Its subcellular localization is in the nucleus and cytoplasm. Up to 2 different isoforms have been reported for this protein. It is reported to be expressed in normal mammary epithelial cells. A member of the IRF protein family, IRF6 is a suspected DNA-binding transcriptional activator. Post-translational modifications have been described, including ubiquitination and phosphorylation. Synonyms for this target antigen include OFC6, PIT, PPS, PPS1, VWS, VWS1, and LPS. IRF6 gene orthologs have been reported in the mouse, rat, bovine, zebrafish, chimpanzee and chicken species. A number of IRF6 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. Immunocytochemistry, Immunofluorescence, and Immunohistochemistry are also common applications.