Anti-ASB12 antibodies are used in the immunodetection of the protein ankyrin repeat and SOCS box containing 12. In humans, the canonical protein has a reported length of 309 amino acid residues and a mass of 33.9 kDa. Up to 2 different isoforms have been reported for this protein. A member of the Ankyrin SOCS box (ASB) protein family, ASB12 is a suspected substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Synonyms for this target antigen include ankyrin repeat and SOCS box protein 12 and ankyrin repeat domain-containing SOCS box protein Asb-12. ASB12 gene orthologs have been reported in the mouse, rat, zebrafish, chimpanzee and chicken species. These ASB12 antibodies are widely used in Western Blot experiments, among other applications.