Anti-NOD3 antibodies enable researchers to detect and measure the NOD3 antigen in biological samples. This target is a reported synonym of the NLRC3 gene, which encodes NLR family CARD domain containing 3. This protein is a reported regulator of the innate immune response. The human version of NOD3 has a canonical amino acid length of 1065 residues and a protein mass of 114.7 kilodaltons, although 4 isoforms have been identified. It is reported to be localized in the cytoplasm of cells. NOD3 is a member of the NLRP protein family.