Anti-NFIC antibodies are used in the immunodetection of the protein nuclear factor I C. In humans, the canonical protein has a reported length of 508 amino acid residues and a mass of 55.7 kDa. Its subcellular localization is in the nucleus. Up to 6 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. A member of the CTF/NF-I protein family, Nfic is known to recognize and bind the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. Synonyms for this target antigen include CTF5, NF-I, NFI, nuclear factor 1 C-type, CCAAT-box-binding transcription factor, and CTF. NFIC gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of Nfic antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA, Immunofluorescence, and Immunohistochemistry are also common applications.