PLEKHG6 encodes the human gene, Pleckstrin homology and RhoGEF domain containing G6. It may also be known as: Pleckstrin homology domain-containing family G member 6; PH domain-containing family G member 6; Myosin-interacting guanine nucleotide exchange factor; MyoGEF; myosin II interacting GEF; pleckstrin homology domain containing, family G (with RhoGef domain) member 6. The encoded protein has an amino acid length of 790 and a mass of 89.0 kDa. Other isoforms may exist. Homologs of this gene exist in other organisms, including: Mouse, Rat, Zebrafish.