Anti-MTA3 antibodies are used in the immunodetection of the protein metastasis associated 1 family member 3. In humans, the canonical protein has a reported length of 594 amino acid residues and a mass of 67.5 kDa. Its subcellular localization is in the nucleus and cytoplasm. Alternative splicing is reported to yield 2 different isoforms for this protein. It is reported to be expressed in germinal centers of lymphoid tissues. MTA3 is known to act as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin. Synonyms for this target antigen include metastasis-associated protein MTA3 and metastasis associated gene family, member 3.