Anti-ME2 antibodies are used in the immunodetection of the protein malic enzyme 2. In humans, the canonical protein has a reported length of 584 amino acid residues and a mass of 65.4 kDa. Its subcellular localization is in the mitochondria. Up to 2 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. A member of the Malic enzymes protein family, ME2 is known to be involved with metabolic processes. Synonyms for this target antigen include NAD-dependent malic enzyme, mitochondrial, NAD-ME, malate dehydrogenase (oxaloacetate-decarboxylating), malic enzyme 2, NAD(+)-dependent, mitochondrial, pyruvic-malic carboxylase, and ODS1. ME2 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish and chimpanzee species. A number of ME2 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA, Immunocytochemistry, Immunofluorescence, and Immunohistochemistry are also common applications.