Anti-ATF2 antibodies are used in the immunodetection of the protein activating transcription factor 2. In humans, the canonical protein has a reported length of 505 amino acid residues and a mass of 54.5 kDa. Its subcellular localization is in the nucleus, mitochondria, and cytoplasm. Up to 8 different isoforms have been reported for this protein. It is widely expressed across many tissue types. A member of the BZIP protein family, ATF2 is reported to be a transcriptional activator, which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Synonyms for this target antigen include CREB-2, HB16, TREB7, cyclic AMP-dependent transcription factor ATF-2, and CRE-BP1. ATF2 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Over 120 citations in the literature describe the use of ATF2 antibodies in research. Western Blot, Immunofluorescence, and Immunohistochemistry are common applications for these antibodies.