Anti-APLF antibodies are used in the immunodetection of the protein aprataxin and PNKP like factor. In humans, the canonical protein has a reported length of 511 amino acid residues and a mass of 57 kDa. Its subcellular localization is in the nucleus and cytoplasm. A member of the APLF protein family, APLF is known to be a histone chaperone involved in single-strand and double-strand DNA break repair. Post-translational modifications have been described, including phosphorylation. Synonyms for this target antigen include PNK and APTX-like FHA domain-containing protein, PNK and APTX-like FHA protein, XRCC1-interacting protein 1, aprataxin- and PNK-like factor, and aprataxin and PNK-like factor. APLF gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some APLF antibodies may have been used in research and have associated citations. ELISA, Western Blot, and Immunohistochemistry are common applications for these antibodies.