Anti-AFG3L2 antibodies are used in the immunodetection of the protein AFG3 like matrix AAA peptidase subunit 2. In humans, the canonical protein has a reported length of 797 amino acid residues and a mass of 88.6 kDa. Its subcellular localization is in the mitochondria. It is ubiquitously expressed across many tissue types. A member of the AAA ATPase protein family; Peptidase M41 protein family, AFG3L2 is reported to be an aTP-dependent protease, which is essential for axonal and neuron development. Synonyms for this target antigen include SCA28, SPAX5, AFG3-like protein 2, AFG3 ATPase family gene 3-like 2, AFG3 ATPase family member 3-like 2, and OPA12. AFG3L2 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of AFG3L2 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. Immunofluorescence and Immunohistochemistry are also common applications.