Anti-ALAS antibodies enable researchers to detect and measure the ALAS antigen in biological samples. This target is a reported synonym of the ALAS1 gene, which encodes 5'-aminolevulinate synthase 1. This protein is known to catalyze the pyridoxal 5'-phosphate (PLP)-dependent condensation of succinyl-CoA and glycine to form aminolevulinic acid (ALA), with CoA and CO2 as by-products. The human version of ALAS has a canonical amino acid length of 640 residues and a protein mass of 70.6 kilodaltons, although 2 isoforms have been identified. It is reported to be localized in the mitochondria of cells and widely expressed in many tissue types. ALAS is a member of the Class-II pyridoxal-phosphate-dependent aminotransferase protein family. Western Blot is a widely used application for the ALAS antibodies listed below. In addition, ELISA is also a common application.