Anti-DTNB antibodies are used in the immunodetection of the protein dystrobrevin beta. In humans, the canonical protein has a reported length of 627 amino acid residues and a mass of 71.4 kDa. Its subcellular localization is in the cell membrane, nucleus, and cytoplasm. Up to 7 different isoforms have been reported for this protein. It is reported to be highly expressed in the brain, kidney and pancreas. A member of the Dystrophin protein family, DTNB is reported to be a scaffolding protein that assembles DMD and SNTA1 molecules to the basal membrane of kidney cells and liver sinusoids (By similarity). Post-translational modifications have been described, including phosphorylation. Synonyms for this target antigen include beta-dystrobrevin. DTNB gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Western Blot is the most common application for the DTNB antibodies listed below. Flow Cytometry, Immunofluorescence, and Immunohistochemistry are also common applications.