Anti-CRTC1 antibodies are used in the immunodetection of the protein CREB regulated transcription coactivator 1. In humans, the canonical protein has a reported length of 634 amino acid residues and a mass of 67.3 kDa. Its subcellular localization is in the nucleus and cytoplasm. Up to 3 different isoforms have been reported for this protein. It is reported to be highly expressed in adult and fetal brain. A member of the TORC protein family, CRTC1 is reported to be a transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Post-translational modifications have been described, including phosphorylation. Synonyms for this target antigen include MECT1, Mam-2, TORC-1, TORC1, WAMTP1, and MAML2. CRTC1 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Over 80 citations in the literature describe the use of CRTC1 antibodies in research. Western Blot is a widely used application for these antibodies. ELISA and Immunofluorescence are also common applications.