TORC1/CRTC1 (C71D11) Rabbit mAb 2587S from Cell Signaling Technology

Product Specs
ItemTORC1/CRTC1 (C71D11) Rabbit mAb
CompanyCell Signaling Technology
Price $339.00 Inquire
Catalog Number2587S
Quantity100 µl
ApplicationsW
ReactivityM, R
TargetTORC1
HostRabbit
NCBI Gene AliasesMAML2, MECT1, Mam-2, TORC-1, TORC1, WAMTP1
ClonalityMonoclonal
NCBI Full Gene NameCREB regulated transcription coactivator 1
Research AreaMetabolism
IsotypeIgG
CloneC71D11
Molecular Weight78

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Relationship between Corvis ST tonometry parameters and mean blur rate in the optic nerve head tissue area in healthy eyesPLoS OneJune 23, 2026Yuta Nakaniida, Fumiko Higashikawa, Kana Tokumo, Shunsuke Nakakura, Ryo Asaoka, Yoshiaki Kiuchi, Hirokazu Sakaguchireviewed and approved by the Ethical Committee for Epidemiology of Hiroshima University (permission No. E-2587). All participants provided written informed consent allowing their clinical data to be stored in the

(2) Targeting CRTC2 reverses STK11 mutant NSCLC tumor resistance to immunotherapyProc Natl Acad Sci U S AApril 28, 2026Dimitri Robay, Ole Ackermann, Laurent Laborde, Xingyi Shi, Federico Oreglia, Ramona Stump, Sabina Ciaghi, Giorgio G. Galli, Laura Holzer, Lorraine Villemin, et al.membranes (Thermo Scientific) and probed with the following antibodies: LKB1 (CST, #3047), CRTC1 (CST, #2587), CRTC2 (Millipore, # MABN695 for mouse samples and Abcam, # ab109081 for human samples), CRTC3 (CST,

(3) Neuronal differentiation and activity drive nucleocytoplasmic shuttling of the intellectual disability kinase TLK2Front Cell NeurosciApril 7, 2026Lubna Nuhu-Soso, Heidi Denton, Darren L. Goffin, Ines Hahn, Gareth J. O. Evans(IF)",Rabbit,A301-257A,Bethyl Anti-TLK2,1:200 (IHC),Rabbit,13979-1-AP,Proteintech Anti-TORC1/CRTC1,"1:1,000 (IF)",Rabbit,2587,Cell Signaling Technology Anti-β-III-tubulin,"1:1,000 (WB)1:500 (IF)",Mouse,801202,Biolegend Anti-β-actin,"1:50,000–1:100,000

(4) Interruption of p38MAPK-MSK1-CREB-MITF-M pathway to prevent hyperpigmentation in the skinInternational Journal of Biological SciencesFebruary 17, 2024Song-Hee Kim, Jiyeon Lee, Jihye Jung, Ga Hyun Kim, Cheong-Yong Yun, Sang-Hun Jung, Bang Yeon Hwang, Jin Tae Hong, Sang-Bae Han, Jae-Kyung Jung, et al.(Cell Signaling Technology, 9197); anti-p-CRTC1 (Cell Signaling Technology, 3359); anti-CRTC1 (Cell Signaling Technology, 2587); anti-p-β-catenin (Cell Signaling Technology, 9567); anti-β-catenin (Cell Signaling Technology, 9562);

(5) Targeting phosphorylation circuits on CREB and CRTCs as the strategy to prevent acquired skin hyperpigmentationInternational Journal of Biological SciencesJanuary 1, 2024Song-Hee Kim, Changseon Na, Cheng-Yong Yun, Jun Gu Kim, Seung Tae Baek, Hyun Jin An, Jae Duk Lee, Seung Wha Lee, Jae-Kyung Jung, Bang Yeon Hwang, et al.(Cell Signaling Technology, 2532); anti-CREB (Cell Signaling Technology, 9197); anti-CRTC1 (Cell Signaling Technology, 2587); anti-CRTC2 (Merck Millipore, ST1099); anti-CRTC3 (Santa Cruz Biotechnology, sc-390712); anti-MITF-M

(6) Fasting produces antidepressant-like effects via activating mammalian target of rapamycin complex 1 signaling pathway in ovariectomized miceNeural Regeneration ResearchMarch 17, 2023Zi-Qian Cheng, Bing-Jin Fan, Zi-Qian Cheng, Jing-Yun Fan, Fang-Yi Zhao, Jing-Yun Cui, Bing-Jin Sunpolyclonal, 1:1000; CST, Cat# 9101, RRID: AB_331646), mTORC1 (rabbit monoclonal, 1:1000; CST, Cat# 2587, RRID:AB_2261091), p70S6 (rabbit polyclonal, 1:1000; CST, Cat# 9202, RRID:AB_331676), S6 (rabbit monoclonal,

(7) Lower body muscle strength, dynapenic obesity and risk of type 2 diabetes –longitudinal results on the chair-stand test from the Survey of Health, Ageing and Retirement in Europe (SHARE)BMC GeriatricsDecember 1, 2022Bernd Kowallhandgrip strength (kg),44.9 ± 9.7,27.5 ± 6.7 CST-5,CST-5,CST-5 Did not feel safe to do the CST-5,2587 (12.7%),4000 (15.5%) Test performed,"17,770 (87.3%)","21,762 (84.5%)" Time for 5 sits and stands (s),11.2

(8) Capsaicin and Zinc Promote Glucose Uptake in C2C12 Skeletal Muscle Cells through a Common Calcium Signalling PathwayInternational Journal of Molecular SciencesFebruary 17, 2022Parisa Vahidi Ferdowsi, Kiran D. K. Ahuja, Jeffrey M. Beckett, Stephen MyerspCREB (Ser133) (cat# 9198S), CREB (cat# 9197S), pTORC1/CRTC1 (Ser151) (cat#3359), TORC1/CRTC1 (cat#2587), HRP-linked secondary antibodies (Anti-rabbit (cat#7074) and Anti-mouse (cat#7076)), and GAPDH (cat#5174)

(9) Disruption of CRTC1 and CRTC2 in Sim1 cells strongly increases high-fat diet intake in female mice but has a modest impact on male micePLOS ONEJanuary 12, 2022Jin Tanaka, Fuka Ishikawa, Tomoki Jinno, Motoki Miyakita, Haruka Miyamori, Tsutomu Sasaki, Takumi Yokokawa, Tsuyoshi Goto, Kazuo Inoue, Shigenobu Matsumura(Yukijirushi, Sapporo, Japan), the sections were incubated overnight with rabbit anti-CRTC1 antibody (#2587, 1: 1000 dilution, Cell Signaling Technology, Danvers, MA, USA) or anti-CRTC2 antibody (#3826, 1: 1000

(10) Loss of presenilin function enhances tau phosphorylation and aggregation in miceActa neuropathologica communicationsSeptember 30, 2021Soto-Faguás CM, Sanchez-Molina P, Saura CA.PSD95 (Cell Signaling, 2507) and CREB-regulated transcription coactivator 1 (CRTC1, Cell Signaling, 2587) and mouse anti-synaptophysin (Sigma, S5768), syntaxin 1 (SantaCruz, sc-12736), β-tubulin (Sigma, T9026),

(11) Integrating pheromonal and spatial information in the amygdalo-hippocampal networkNature communicationsSeptember 6, 2021Villafranca-Faus M, Vila-Martín ME, Esteve D, Merino E, Teruel-Sanchis A, Cervera-Ferri A, Martínez-Ricós J, Lloret A, Lanuza E, Teruel-Martí V.Akt (9272, Cell Signaling Technology, 1:1000); pAkt (9271, Cell Signaling Technology, 1:1000); CRTC1 (2587, Cell Signaling Technology, 1:1000); pCREB (9191, Cell Signaling Technology, 1:500); GSK3β (JM-3494-100,

(12) Transcriptional co-activator regulates melanocyte differentiation and oncogenesis by integrating cAMP and MAPK/ERK pathwaysCell reportsMay 18, 2021Ostojić J, Yoon YS, Sonntag T, Nguyen B, Vaughan JM, Shokhirev M, Montminy M.1.1.6r4) (Saldanha, 2004). Antibodies Rabbit anti-CREB serum (244, in-house), rabbit anti-CRTC1 (C71D11, 2587, CST), rabbit anti-CRTC2 serum (6865, in-house), rabbit anti-CRTC3 (C35G4, 2720, CST), rabbit anti-CRTC3-pSer391

(13) CREB Family Transcription Factors Are Major Mediators of BDNF Transcriptional Autoregulation in Cortical NeuronsThe Journal of NeuroscienceFebruary 12, 2020Eli-Eelika Esvald, Jürgen Tuvikene, Alex Sirp, Sudarshan Patil, Clive R. Bramham, Tõnis TimmuskImmunocytochemistry was performed as described by Koppel et al. (2018) using CRTC1 antibody (1:1500, catalog #2587, lot 3, Cell Signaling Technology) and goat anti-rabbit IgG conjugated with Alexa-488 (1:2000, Invitrogen)

(14) Stem Cell Factor-Inducible MITF-M Expression in Therapeutics for Acquired Skin HyperpigmentationTheranosticsJanuary 1, 2020Yun CY, Roh E, Kim SH, Han J, Lee J, Jung DE, Kim GH, Jung SH, Cho WJ, Han SB, et al.ab12039), CREB (Cell Signaling, 9197), p-CREB at Ser-133 (Cell Signaling, 9198), CRTC1 (Cell Signaling, 2587), p-CRTC1 at Ser-171 (Cell Signaling, 3359), SOX10 (Santa Cruz, sc-17342), c-Raf (Cell Signaling, 9422),

(15) Hyaluronic acid-functionalized gelatin hydrogels reveal extracellular matrix signals temper the efficacy of erlotinib against patient-derived glioblastoma specimensBiomaterialsOctober 1, 2019Sara Pedron, Gabrielle L. Wolter, Jee-Wei E. Chen, Sarah E. Laken, Jann N. Sarkaria, Brendan A. C. Harleyall from Cell Signaling, Danvers, MA): anti-β-actin (#4967); PDGF Receptor β (#4564); TORC1/CRTC1 (#2587); Phospho-p44/42 MAPK (Erk1/2) (#9101); p44/42 MAPK (Erk1/2) (#9102); PDGF Receptor α (#3164); Phospho-Stat3

(16) Nuclear Entry of CRTC1 as Druggable Target of Acquired Pigmentary DisorderTheranosticsJanuary 1, 2019Yun CY, Hong SD, Lee YH, Lee J, Jung DE, Kim GH, Kim SH, Jung JK, Kim KH, Lee H, et al.(Cell Signaling, 9198), CREB (Cell Signaling, 9197), p-CRTC1 (Cell Signaling, 3359), CRTC1 (Cell Signaling, 2587), 14-3-3 (Santa Cruz, sc-1657), p-β-catenin (Cell Signaling, 9567), β-catenin (Cell Signaling, 9562),

(17) Rapamycin induces autophagy to alleviate acute kidney injury following cerebral ischemia and reperfusion via the mTORC1/ATG13/ULK1 signaling pathwayMolecular medicine reportsDecember 1, 2018Su Y, Lu J, Gong P, Chen X, Liang C, Zhang J.anti-autophagy-related 13 (Atg13; cat. no. 13273), anti-mammalian target of rapamycin complex 1 (mTORC1; cat. no. 2587), anti-unc-51 like autophagy activating kinase 1 (ULK1; cat. no. 8054) and anti-phosphorylated (p-)ULK1

(18) Expression of PD-1 and PD-L1 increase in consecutive biopsies in patients with classical Hodgkin lymphomaPLOS ONESeptember 27, 2018Peter Hollander, Rose-Marie Amini, Beatrice Ginman, Daniel Molin, Gunilla Enblad, Ingrid Glimelius

(19) Influence of Phosphatidylinositol-3-Kinase/Protein Kinase B-Mammalian Target of Rapamycin Signaling Pathway on the Neuropathic Pain Complicated by Nucleoside Reverse Transcriptase Inhibitors for the Treatment of HIV InfectionChinese Medical JournalAugust 5, 2018Hao Cheng, Liang-Yu Wuantibodies were purchased from Cell Signaling Technology (Massachusetts, USA). Rabbit anti-mTORC1 (lot No: 2587) and rabbit anti-phospho-mTORC1 (lot No: 5536) antibodies were purchased from Abcam (Cambridge, UK).

(20) Falls and Fall-Related Injuries Among US Adults Aged 65 or Older With Chronic Kidney DiseasePreventing Chronic DiseaseJune 24, 2018Brandon M. Kistler, Jagdish Khubchandani, Gina Jakubowicz, Kenneth Wilund, Jacob SosnoffVirnig BA. Risk of pelvic fractures in older women following pelvic irradiation. JAMA 2005;294(20):2587–93. 21. Bennell K, Dobson F, Hinman R. Measures of physical performance assessments: Self-Paced Walk

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TORC1/CRTC1 (C71D11) Rabbit mAb

TORC1/CRTC1 (C71D11) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

Citations (38)

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TORC1/CRTC1 (C71D11) Rabbit mAb from Cell Signaling Technology

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