Anti-CASZ1 antibodies are used in the immunodetection of the protein castor zinc finger 1. In humans, the canonical protein has a reported length of 1759 amino acid residues and a mass of 190.1 kDa. Its subcellular localization is in the nucleus. Up to 2 different isoforms have been reported for this protein. It is found to be expressed in the heart, lung, skeletal muscle, pancreas, testis, small intestine, and stomach, but it is not detectable in the adult brain. CASZ1 is known to be involved with the regulation of transcription and regulation of neuron differentiation.
The CASZ1 marker can be used to identify Eccentric Medium Spiny Neurons and Medulla Oblongata Splatter Neurons.* Synonyms for this target antigen include CST, ZNF693, dJ734G22.1, zinc finger protein castor homolog 1, and CAS11. CASZ1 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of CASZ1 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA, Immunofluorescence, and Immunohistochemistry are also common applications.
*HuBMAP Human Reference Atlas v1.4