Anti-SIL1 antibodies are used in the immunodetection of the protein SIL1 nucleotide exchange factor. In humans, the canonical protein has a reported length of 461 amino acid residues and a mass of 52.1 kDa. Its subcellular localization is in the ER. It is reported to be highly expressed in tissues which produce large amounts of secreted proteins such as kidney, liver and placenta. A member of the SIL1 protein family, SIL1 is known to be required for protein translocation and folding in the endoplasmic reticulum (ER). Post-translational modifications have been described, including N-glycosylation and ubiquitination. Synonyms for this target antigen include BiP-associated protein, SIL1 homolog, endoplasmic reticulum chaperone, SIL1-like protein endoplasmic reticulum chaperone, and nucleotide exchange factor SIL1. SIL1 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of SIL1 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. Immunofluorescence and Immunohistochemistry are also common applications.