Anti-RTL3 antibodies are used in the immunodetection of the protein retrotransposon Gag like 3. In humans, the canonical protein has a reported length of 475 amino acid residues and a mass of 52.8 kDa. Its subcellular localization is in the nucleus. RTL3 is believed to function as a a transcriptional regulator. Synonyms for this target antigen include Sushi-Ichi retrotransposon homolog 9, mammalian retrotransposon-derived 3, zinc finger CCHC domain-containing protein 5, zinc finger CCHC-type containing 5, and retrotransposon Gag-like protein 3. RTL3 gene orthologs have been reported in the mouse, rat, bovine and chimpanzee species.