Anti-DNMT3L antibodies are used in the immunodetection of the protein DNA methyltransferase 3 like. In humans, the canonical protein has a reported length of 386 amino acid residues and a mass of 43.6 kDa. Its subcellular localization is in the nucleus. Up to 2 different isoforms have been reported for this protein. It is reported to be expressed at low levels in several tissues including testis, ovary, and thymus. DNMT3L is known to be involved with chorionic trophoblast cell differentiation and in utero embryonic development. Synonyms for this target antigen include DNA (cytosine-5-)-methyltransferase 3-like, cytosine-5-methyltransferase 3-like protein, human cytosine-5-methyltransferase 3-like protein, and DNA (cytosine-5)-methyltransferase 3-like. DNMT3L gene orthologs have been reported in the mouse, rat, bovine and chimpanzee species.