Anti-RNF6 antibodies are used in the immunodetection of the protein ring finger protein 6. In humans, the canonical protein has a reported length of 685 amino acid residues and a mass of 78.1 kDa. Its subcellular localization is in the nucleus and cytoplasm. Up to 3 different isoforms have been reported for this protein. It is reported to be weakly expressed in peripheral blood, spleen, prostate, testis and ovary. A member of the RNF12 protein family, RNF6 is known to be involved with the regulation of transcription and protein ubiquitination. Synonyms for this target antigen include RING-H2 protein RNF-6, RING-type E3 ubiquitin transferase RNF6, ring finger protein (C3H2C3 type) 6, and E3 ubiquitin-protein ligase RNF6. RNF6 gene orthologs have been reported in the mouse, rat, bovine, zebrafish, chimpanzee and chicken species. A number of RNF6 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunofluorescence are also common applications.