Anti-PDXP antibodies are used in the immunodetection of the protein pyridoxal phosphatase. In humans, the canonical protein has a reported length of 296 amino acid residues and a mass of 31.7 kDa. Its subcellular localization is in the cell membrane and cytoplasm. It is ubiquitously expressed across many tissue types. A member of the HAD-like hydrolase protein superfamily, PDXP is known to function as a pyridoxal phosphate (PLP) phosphatase, which also catalyzes the dephosphorylation of pyridoxine 5'-phosphate (PNP) and pyridoxamine 5'-phosphate (PMP), with order of substrate preference PLP > PNP > PMP and therefore plays a role in vitamin B6 metabolism. Synonyms for this target antigen include PLP phosphatase, pyridoxal (pyridoxine, vitamin B6) phosphatase, pyridoxal phosphate phosphatase, testicular secretory protein Li 36, and chronophin. PDXP gene orthologs have been reported in the mouse, rat, bovine and chicken species. A number of PDXP antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. In addition, ELISA is also a common application.