Anti-USP25 antibodies are used in the immunodetection of the protein ubiquitin specific peptidase 25. In humans, the canonical protein has a reported length of 1055 amino acid residues and a mass of 122.2 kDa. Its subcellular localization is in the nucleus and cytoplasm. Up to 3 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. A member of the Peptidase C19 protein family, USP25 is a type of deubiquitinating enzyme that hydrolyzes ubiquitin moieties conjugated to substrates and thus, functions to process newly synthesized Ubiquitin, to recycle ubiquitin molecules or to edit polyubiquitin chains and prevents proteasomal degradation of substrates. Synonyms for this target antigen include ubiquitin carboxyl-terminal hydrolase 25, USP on chromosome 21, deubiquitinating enzyme 25, ubiquitin thioesterase 25, ubiquitin thiolesterase 25, and USP21. A number of USP25 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.