Anti-UPF3B antibodies are used in the immunodetection of the protein UPF3B regulator of nonsense mediated mRNA decay. In humans, the canonical protein has a reported length of 483 amino acid residues and a mass of 57.8 kDa. Its subcellular localization is in the nucleus and cytoplasm. Up to 2 different isoforms have been reported for this protein. It is reported to be expressed in the testis, uterus, prostate, heart, muscle, brain, spinal cord and placenta. A member of the RENT3 protein family, UPF3B is known to be involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by associating with the nuclear exon junction complex (EJC) and serving as link between the EJC core and NMD machinery. Synonyms for this target antigen include UPF3 regulator of nonsense transcripts homolog B, UPF3B pseudogene 1, UPF3B pseudogene 2, UPF3B pseudogene 3, and regulator of nonsense transcripts 3B. A number of UPF3B antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. In addition, Immunohistochemistry is also a common application.