Anti-Actinin, alpha 4 antibodies are used for the immunodetection of the protein encoded by the ACTN4 gene. In humans, the canonical protein has a reported length of 911 amino acid residues and a mass of 104.9 kDa. Its subcellular localization is in the nucleus and cytoplasm. Alternative splicing is reported to yield 3 different isoforms for this protein. It is widely expressed across many tissue types. A member of the Alpha-actinin protein family, it is known to be involved with cytoskeleton organization and the regulation of cell migration. Other names for this target antigen include FSGS, FSGS1, alpha-actinin-4, focal segmental glomerulosclerosis 1, non-muscle alpha-actinin 4, and ACTININ-4. Gene orthologs have been identified in the mouse, rat, bovine, frog, chimpanzee and chicken species. A number of Actinin, alpha 4 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.