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Nucleic Acid Purification
Automated DNA/RNA/Protein Purification Systems
Automated DNA/RNA Extraction Systems
Maxwell RSC Instrument
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Maxwell RSC Instrument
Maxwell RSC Instrument
Maxwell RSC Instrument from Promega
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Citations:
(892)
Figures:
(1)
Supplier Page
Supplier Page from
Promega for
Maxwell RSC Instrument
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Description
The Maxwell RSC Instrument is a platform for automated extraction of nucleic acid from a range of sample types. Extraction methods use sample lysis and binding to paramagnetic particles followed by washing steps and elution.
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Maxwell RSC Instrument
Company
Promega
Price
Supplier Page
View Company Product Page
Catalog Number
AS4500
Quantity
EA
Processing Time
30 to 60 min (depending on sample type and method)
Capacity
Up to 16
Dimensions
(WxDxH) 330.2 x 345.2 x 299.7 mm (13 x 13.6 x 11.8 in)
UV Lamp
Avg. lifetime approximately 6,000 hrs
Molecular Weight
~85kDa
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Promega
2800 Woods Hollow Rd
Madison
,
WI
53711
United States
Phone
: Tel: +1 (608) 274-4330
Fax: +1 (608) 277-2516
Email: custserv@promega.com
techserv@promega.com
Company Profile
Website:
http://www.promega.com
Citations (892)
(1)
High-throughput analyses of Phocaeicola vulgatus reveal fitness determinants for gut colonization and during colitis
Gut Microbes
December 31, 2026
Nazik M. Elmekki, Michael J. Coyne, Katia Flores, Leonor García-Bayona, Laurie E. Comstock
Family Institute Microbiome
Metagenomics
Facility (DFI-MMF). Following nucleic acid recovery using a
Maxwell RSC instrument
(
Promega Corporation
, Madison, WI), DNAse treatment and elution, the samples were quantified using Qubit
(2)
Can GM soybean be reliably quantified after screening? A risk-based approach for optimizing GMO testing workflow
GM Crops Food
December 31, 2026
Davide La Rocca, Katia Spinella, Pietro Franceschi, Daniela Verginelli, Sara Ciuffa, Marisa Misto, Cinzia Quarchioni, Cristiana Fusco, Stefania Peddis, Pamela Bonini,
et al.
DNA Estractor FAST (©Generon S.p.A, Italy) and later with the RSC PureFood GMO by using an extractor
Maxwell®RSC Instrument
(
Promega
Madison, WI, USA), according to the manufacturer’s instructions. As a test portion, 2 g of
(3)
Evaluation of wastewater SARS-CoV-2 surveillance for monitoring COVID-19 trends and early warning in Sweden, 2023-2024
PLoS One
September 21, 2026
Anna Ohlson, Moa Rehn, Sharon Kühlmann Berenzon, Erik Sturegård, Rakel Brodin, Anna J. Székely, Sofia Persson, Ilias Galanis
wastewater using the
Maxwell® RSC Enviro TNA kit
(
Promega
,
AS1831
) on the
Maxwell® RSC instrument
(
AS4500
) with the PureFood GMO and Authentication program, as previously described [21]. Each sample was split
(4)
FGFR2 Fusions in Pancreatobiliary and Ampullary Cancers: High Detection Rate in FFPE Specimens of Intrahepatic Cholangiocarcinoma with Limited RNA Yields Using Amplicon-Based NGS Assay
Curr Oncol
September 15, 2026
Simon Guertin, Niloofar Sina, Ken Kron, Kenneth J. Craddock, Amy McCarty, David M. Hwang, Weei-Yuarn Huang
subjected to nucleic acid extraction using the Promega Maxwell RSC system (
Promega
, Madison, WI, USA; Cat #
AS4500
). DNA and RNA were quantified using Qubit 4 (Thermo Fisher Scientific Inc., Waltham, MA, USA; Cat #
(5)
CpG hypermethylation and WNT/AP-1 cooperativity define the epigenetic landscape and a clinical subgroup of high-risk pediatric adrenocortical carcinoma
Nat Commun
September 14, 2026
Victoria E. Fincke, Maurice Loßner, Marina Kunstreich, Nic G. Reitsam, Irmengard Sax, Marlena Mucha, Felix Dorn, Lorenz C. Helmschrott, Maria D. Hernandez Ramirez, Sebastian Dintner,
et al.
buffer. Quantitative
RT-PCR
Total RNA was isolated using the
Maxwell RSC simplyRNA Cells Kit
on the
Maxwell RSC instrument
(
Promega
) according to the manufacturer’s instructions. RNA quantity was assessed by Qubit (Thermo Fisher
(6)
Intra-CNS AAV9-GBA1 delivery yields species and route of administration differences in safety and transgene expression
Molecular Therapy Advances
September 10, 2026
Ana Claudia Amaral, Branka Grubor, Davide Gianni, Lee Koetzner, Neeta Abraham, Shawn Bourque, Danielle Brown, Yi Chen, Kay-Ellen Chicoine, Pete Clarner,
et al.
were added to the tubes, samples were homogenized using a Geno Grinder, and DNA was extracted using a
Maxwell RSC instrument
according to the manufacturer’s instruction. DNA was quantified, and purity was assessed using a SpectraMax
(7)
Co-delivery of lentiviral vectors and Cas9-containing virus-like particles enables rapid, scalable manufacture of gene-edited CAR T cells
Mol Ther Adv
September 10, 2026
Francesca Ferrara, Matthew M. Wielgosz, Jeoungeun J. Park, Matthew Bauler, Chris Wincek, Nataly Mier, Yin Su, Li Tang, Brandon R. Lowe, Jordan A. Beard,
et al.
using the
Maxwell RSC Viral Total Nucleic Acid Purification Kit
(
Promega
, Madison, WI, USA) and the
Maxwell RSC Instrument
(
Promega
). Library preparation for
Illumina sequencing
was performed at the St. Jude Children’s Research
(8)
Bile acid sequestration reveals microbiome remodeling that dominates FXR signaling to shape host responses to enteric infection
PLoS Pathog
September 8, 2026
Anahita Mansouripour, Drew R. Seeger, Meredith Parmer, Peddanna Kotha, Anton M. Golovko, Mikhail Y. Golovko, Shahram Solaymani-Mohammadi
Promega
Maxwell RSC simplyRNA Tissue Kit
(Promega, Madison, WI, USA) using a
Maxwell RSC instrument
AS4500
(
Promega
) according to the manufacturer’s instructions. Briefly, jejunal tissues were homogenized in
(9)
First record of Ornithocoris pallidus (Hemiptera: Cimicidae) associated with Hyacinth macaw (Anodorhynchus hyacinthinus) nest in the Brazilian Pantanal
Int J Parasitol Parasites Wildl
September 4, 2026
Ivanise Paula Sobota, Maria Eduarda Monteiro Nascimento, Fernanda Fontoura, Ana Cecília de Paula Lourenço Rocha, Vitor Morais de Oliveira, Herbert Patric Kellermann Cleveland, Leila Sabrina Ullmann, Carlos Alberto Nascimento Ramos, Rafael Antonio do Nascimento Ramos, Fernando Paiva,
et al.
and Animal Science (FAMEZ-UFMS). Extraction was performed using an adapted, automated method with the
Maxwell® RSC instrument
(
Promega
) in conjunction with the
Maxwell® RSC PureFood GMO and Authentication Kit
(Catalog No.
AS1600
;
(10)
Genetic variants associated with clinical characteristics and atopies in eosinophilic esophagitis
Journal of Allergy and Clinical Immunology: Global
September 1, 2026
Leticia Rodríguez-Alcolado, Marcos Navares-Gómez, Sergio Casabona-Francés, Javier Molina-Infante, Danila Guagnozzi, Paula Soria-Chacartegui, Sara Feo-Ortega, Laura Arias-González, Macarena Torres-Larrubia, Ronald Llerena-Castro,
et al.
subcohorts.
Genotyping
DNA extraction was performed using the
Maxwell RSC Whole Blood DNA kit
(
Promega
, Madison, Wis) in a
Maxwell RSC instrument
(
Promega
) following the manufacturer’s instructions.
Genotyping
was performed using the
QuantStudio 12K Flex Real-Time PCR System
(11)
SINE Insertion in LAMA3 in Dogs With Junctional Epidermolysis Bullosa
Anim Genet
August 23, 2026
Sarah Kiener, Ronnie Kaufmann, Ori Brenner, Vidhya Jagannathan, Tosso Leeb
included in the study was isolated from EDTA blood with the
Maxwell RSC Whole Blood DNA Kit
using a
Maxwell RSC instrument
(
Promega
, Dübendorf, Switzerland). One of the affected female
dogs
was whole‐genome sequenced as follows.
(12)
Linking the Degree of Intrauterine Growth Restriction to Alterations in Metabolism, Energy Reserves, and Gut Health in Newborn Piglets
Journal of Animal Science
August 17, 2026
Pau Salgado-López, Júlia Suppi, Katelyn N Gaffield, Mike D Tokach, Jaume Coma, Josep Gasa, David Solà-Oriol
extracted with the
Maxwell® RSC simplyRNA Tissue Kit
(
Promega Corporation
, Madison, Wisconsin, USA) on a
Maxwell® RSC instrument
(
Promega Corporation
, Madison, Wisconsin, USA), following the manufacturer’s instructions. RNA quantity
(13)
Applicability of Nanopore-only whole-genome sequencing for Pseudomonas aeruginosa outbreak investigation in the ICU setting: a multicentric study
Journal of Clinical Microbiology
August 12, 2026
J. Dingemans, S. Vandersanden, P. Hilkens, J. Godelaine, K. Magerman, F. Crombé, D. De Geyter, A. Boel, P. Bruynseels, J. Frans,
et al.
suspensions of plate-grown bacterial cultures in DNA/RNA shield using the RSC
Cultured Cells
DNA kit on the
Maxwell RSC instrument
(
Promega
) according to the manufacturer’s instructions. DNA concentration was assessed using the
Qubit fluorometer
(14)
NUP153 immunoreactivity in neuroendocrine neoplasms supports the diagnosis of NET versus NEC and is modulated by post-translational modifications
J Neuroendocrinol
August 12, 2026
Sven Mattern, Arslan Ali, Vanessa Hollfoth, Eyyub Bag, Katharina Kluthe, Esther Herpel, Frank Bergmann, Thomas Muley, Michael Meister, Judith Lehmann-Koch,
et al.
was extracted from macrodissected 5 μm paraffin sections using the
Maxwell® RSC RNA FFPE Kit
and the
Maxwell® RSC Instrument
(
Promega
, Madison, WI, USA) according to the manufacturer's instructions. For further information, see
(15)
The telomeric DNA damage response as a therapeutic target in idiopathic pulmonary fibrosis
EMBO Molecular Medicine
August 12, 2026
Francesca Rossiello, Giada Cicio, Sara Sepe, Alexandra Mancheno-Ferris, Valeria Cancila, Arianna Castellini, Federica Rey, Giorgio Bertolazzi, Alessia Oppezzo, Eugenia Marinelli,
et al.
then added, and samples were incubated at 56 °C for 10 min. RNA extraction was then performed using
Maxwell® RSC Instrument
(
Promega
), with
Maxwell® RSC simplyRNA Tissue Kit
(
Promega
, AS134), following the manufacturer’s instructions.
(16)
Patterned ELR‐Gelatin Hydrogels Enable Rapid Endothelial Monolayer Formation via Bioactive Matrix Chemistry and Surface Topography
Advanced Healthcare Materials
August 10, 2026
Jagoda Litowczenko, Yannick Richter, Martyna Michalska, Piotr Paczos, Karine Tadevosyan, Daniel Uribe, Jose Carlos Rodriguez‐Cabello, Ioannis Papakonstantinou, Angel Raya
Quantitative Real‐Time Polymerase Chain Reaction
(
qRT‐PCR
) Total RNA was extracted from iPSC‐ECs using Maxwell RSC simplyRNA Cells kits on a
Maxwell RSC instrument
(
Promega
). cDNA was synthesized from 1 µg RNA using Transcriptor First Strand cDNA kit (Roche).
qPCR
(17)
Environmental tuning of thyroid hormone signaling drives developmental plasticity
Sci Adv
August 7, 2026
Marcela Herrera, Saori Miura, Zoé Chamot, Mathieu Reynaud, Emma Gairin, Roger Huerlimann, Timothy Ravasi, Laurence Besseau, Yann Gibert, David Lecchini,
et al.
RNA was extracted from whole larvae using the
Maxwell RSC simplyRNA Tissue Kit
(
Promega
, USA) on the
Maxwell RSC instrument
, following the manufacturer’s instructions. RNA quantity and quality were assessed with an Invitrogen
(18)
The Impact of Molecular Profile Changes and Other Histopathological Parameters on Endometrial Cancer Recurrence
Cancers (Basel)
July 30, 2026
Robert Rottscholl, Johanna Winkelmann, Konstantin Fritz, Verena Gassenmaier, Isabell Goetting, Annette Staebler, Annika Simma, Sascha Hoffmann, Birgitt Schoenfisch, Stefan Kommoss,
et al.
from macrodissected 5 µm paraffin sections was performed using the
Maxwell® RSC DNA FFPE Kit
and the
Maxwell® RSC Instrument
(
Promega
, Madison, WI, USA) and followed by
DNA quantification
with the
Qubit Fluorometer
employing
(19)
Strong catchment-specific structuring of Swedish wastewater microbiomes in a paired two-timepoint metagenomic survey
Frontiers in Microbiology
July 29, 2026
Dhananjay Mukhedkar, Milan S. Stosic, Anna J. Székely, Ekaterina Avershina, Laila Sara Arroyo Mühr
influent wastewater using the
Maxwell® RSC Enviro TNA Kit
(
Promega Corporation
, Madison, WI, USA) on the
Maxwell® RSC instrument
(
Promega Corporation
, Madison, WI, USA), following the manufacturer’s instructions with the PureFood
(20)
Genomic Alterations in Quadruple-Negative Breast Cancer Tumors
International Journal of Molecular Sciences
July 25, 2026
Carolina Jaliffa, Uwe Rogel, Cornelia Leo, Gad Singer
slices. Total nucleic acid (TNA) from
tumor
areas was isolated using the
Maxwell® RSC RNA FFPE kit
on the
Maxwell® RSC instrument
(
Promega
, Madison, WI, USA) according to the manufacturer’s instructions. DNA was quantified using the
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Maxwell RSC Instrument from Promega
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