MagNA Pure 96 Instrument from Roche

Product Specs
ItemMagNA Pure 96 Instrument
CompanyRoche
Price Get Pricing Get Quote for this Product
Catalog Number05195322001
QuantityEA
CapacityMaximum 10 Samples per run
Dimensions(WxDxH) 136 x 81.5 x 100 cm (53.9 x 31.5 x 39.4 inches)
ApplicationsAutomated Nucleic Acid Purification
Volume50 to 500 µl with 96 reactions per run / 1,000 µl with 48 reactions per run
Throughput50-60 minutes for 200 µl sample volumes \ Approx. 80-90 minutes for 500 µl sample volumes

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Roche

Roche Diagnostics Corporation P.O. Box 50414 9115 Hague Road

Indianapolis, Indiana

United States

Phone: +1-800-262-1640
Fax: +1-800-428-2883
Technical Service Phone: +1-800-262-4911

Company Profile

Website: sequencing.roche.com

(1) Adaptation and validation of an influenza a subtyping panel for detection of H1pdm09, H3 and H5 on a high-throughput RT-qPCR systemSci RepApril 20, 2026Katja Giersch, Dominik Nörz, Moritz Grunwald, Hui Ting Tang, Lisa Sophie Pflüger, Susanne Pfefferle, Anne Pohlmann, Martin Beer, Martin Aepfelbacher, Timm Harder, et al.200 µl nasopharyngeal swab samples by using the MagNA Pure 96 DNA and Viral NA Small Volume Kit and a MagNA-Pure 96 instrument (Roche, Basel, Switzerland) according to the manufacturer´s instructions and manual qPCR was performed

(2) Clinical performance of two commercial PCR assays for the detection of macrolide resistance in Mycoplasma pneumoniaeJournal of Clinical MicrobiologyMarch 11, 2026Nadège Hénin, Alicia Silvant, Marie Gardette, Carla Balcon, Jennifer Guiraud, Cécile Bébéar, Sabine Pereyreclinical specimens or strain cultures using the MagNA Pure 96 DNA and Viral NA Small Volume Kit on the MagNA Pure 96 Instrument (Roche Diagnostics, Meylan, France), yielding an elution volume of 100 µL. Prior to extraction, 10 µL

(3) R-loop editing by DNA cytosine deaminase APOBEC3B modulates the activity of oestrogen receptor enhancersNature CommunicationsFebruary 18, 2026Chi Zhang, Yu-jing Lu, Bingjie Chen, Zhiyan Bai, Qiaoxi Zeng, Alexia Hervieu, Marco P. Licciardello, Konstantinos Mitsopoulos, Bissan Al-Lazikani, Marcello Tortorici, et al.package ComplexHeatMap85. RNA-seq and quantification Total RNA from T47D cells were extracted using the MagNA pure 96 instrument (Roche), and RNA integrity number (RIN) was determined by BioAnalyzer 2100 (Agilent). RNA libraries

(4) Routine use of a spike‐in DNA in‐process control for foetal RHD genotyping: Testing the real‐world effectiveness of this ‘canary’Vox SanguinisFebruary 10, 2026Renske M. van ’t Oever, Heleen Woortmeijer, Ahmad Javadi, Aicha Ait Soussan, Barbera Veldhuisen, Claudia C. Folman, C. Ellen van der Schoot, Erik H. van Beers, Masja de Haasspike‐in threshold used in daily practice after implementation. This plate was then processed with the MagNa Pure 96 Instrument (Roche Holding, Basel, Switzerland) for DNA extraction, using the Viral NA Large Volume Kit (Roche),

(5) Development of a Fully Automated, High-Throughput Molecular Assay for Detection of Rat Hepatitis E Virus in Routine DiagnosticsJ Med VirolFebruary 9, 2026Jessica Panajotov, Katja Giersch, Lisa Sophie Pflüger, Dominik Nörz, Moritz Grunwald, Hui Ting Tang, Marco Kaiser, Sven Pischke, Rainer G. Ulrich, Susanne Pfefferle, et al.saline (PBS, Pan Biotech GmbH, Aidenbach, Germany). Nucleic acids from standard were extracted on a MagNA‐Pure 96 instrument (Roche Diagnostics) and quantified by digital‐PCR using the Qiacuity (Qiagen, Hilden, Germany) digital‐PCR

(6) Two TaqMan real-time quantitative PCR assays for the detection of Alongshan virus, a new member of the tick-borne Flaviviridae familyAccess MicrobiolFebruary 9, 2026Onya Opota, Florian Tagini, Valentin Loup, Zahera Dance, Valeria Cagno, Jakub Kubacki, Gilbert Greubfrom the Swiss study of I. ricinus. Nucleic acid extraction Total nucleic acids were extracted on a MagNA Pure 96 instrument (Roche) using the kit MagNA Pure 96 DNA and Viral NA Small Volume. Master mix, primers, probes, plasmids,

(7) Prevalence of chronic viral hepatitis B, D among Mongol migrants in Sweden compared to a sex- and age-matched native Mongol cohortBMC Infectious DiseasesJanuary 16, 2026Delgersaikhan Zulkhuu, Habiba Kamal, Sanjaasuren Enkhtaivan, Ochirmaa Narantsogt, Ganbolor Jargalsaikhan, Munguntsetseg Batkhuu, Byambasuren Ochirsum, Marcus Ahl, Karin Lindahl, Michael Ingre, et al.following nucleic acid extraction using the MagNA Pure 96 DNA and Viral NA Small Volume Kit on the MagNA Pure 96 instrument (Roche Diagnostics GmbH, Germany). HBV-DNA and HCV-RNA levels were quantified using the Cobas HBV, and

(8) Optimization of Cell Culture for Human Adenovirus Isolation and PropagationJugan Geongang Gwa JilbyeongDecember 4, 2025Dongju Kim, Jeong-Min Kim, SangHee Woo, Nam-Joo Lee, Il-Hwan Kim, Eun-Jin Kimpost-inoculation, 200 µl of the supernatant was collected from each sample. Nucleic acids were extracted using the MagNA Pure 96 Instrument (Hoffmann-La Roche Ltd.), and gene amplification was performed using the PowerChekTM Adenovirus Real-time

(9) Unraveling the genome-wide repertoire of the novel chromosomally encoded mcr-8.6 gene variant in Klebsiella michiganensis isolated from manureFront MicrobiolDecember 3, 2025Rani Rivière, Pedro Teixeira, Catarina Silva, Miguel Ramos, Elsa Dias, Vera Manageiro, Manuela CaniçaWhole-genome sequencing Genomic DNA was extracted from a freshly grown overnight culture using the MagNA Pure 96 instrument (Roche, Manheim, Germany) and quantified with a Qubit™ 4 fluorometer (Thermo Scientific, Waltham, USA)

(10) First report of sporotrichosis by Sporothrix brunneoviolaceaMedical Mycology Case ReportsDecember 1, 2025Mariana Rodrgiues Trápaga, Bram Spruijtenburg, Bruna Jacomel, Jéssica Estefânia Dávila Hidalgo, Karine Ortiz Sanchotene, Fabiana Fedatto Bernardon, Bruna Muradás Esperon, Vanice Rodrigues Poester, Theun de Groot, Eelco F.J. Meijer, et al.DNA was extracted with the MagNA Pure and Viral NA Small Volume kit, Pathogen 200SV protocol and the MagNA Pure 96 instrument (all Roche Diagnostics GmbH, Mannheim, Germany) according to manufacturers’ instructions. Genomic libraries

(11) The rise of Candidozyma auris in Czechia: three clades, prosthetic joint infection and fluconazole resistance development, 2022 to 2024EurosurveillanceNovember 14, 2025Bram Spruijtenburg, Jacques F Meis, Norman van Rhijn, Martina Čurdová, Eva Kašperová, Petr Vašek, Lucie Bartoníčková, Jan Kubele, Petra Olišarová, Kateřina Svobodová, et al.(Applied Maths, Sint-Martems-Latem, Belgium) as previously described [13]. For WGS, DNA was extracted on a MagNA Pure 96 instrument (Roche Diagnostics, Mannheim, Germany) using the Small Volume protocol. Next, genomic libraries were

(12) Validation of H5 influenza virus subtyping RT-qPCR assay and low prevalence of H5 detection in 2024–2025 influenza virus seasonJournal of Clinical MicrobiologyNovember 12, 2025David J. Bacsik, Margaret G. Mills, Luke D. Monroe, Cassey Spring, Ailyn C. Perez-Osorio, Jonathan C. Reed, Ferric C. Fang, Lori Bourassa, Pavitra Roychoudhury, Katharine H. D. Crawford, et al.were included with each assay. RNA extraction RNA was extracted from clinical specimens on a Roche MagNA Pure 96 instrument using the Viral NA Small Volume Kit (06543588001). For each sample, 200 µL of specimen was used as input

(13) Comparative Efficacy of Horse and Chicken Serum for the In Vitro Cultivation of Mycoplasma hyorhinis Clinical IsolatesPathogensOctober 19, 2025Yi-Chia Li, Yu-Wei Tseng, Wei-Hao Lin, Chao-Nan Lin, Ming-Tang Chiouextracted from 200 µL of culture using the MagNA Pure 96 DNA and Viral NA Small Volume Kit on an automated MagNA Pure 96 Instrument (Roche, Mannheim, Germany), according to the manufacturer’s protocol. The nucleic acid was eluted in

(14) Atlantic Salmon Alevins Experimentally Exposed to Salmon Gill Poxvirus Become Infected, With the Virus Targeting Epithelial Cells in the Gills, Oral Cavity and SkinJournal of Fish DiseasesOctober 1, 2025Marit Måsøy Amundsen, Haitham Tartor, Kristrun Kristþórsdóttir, Snorre Gulla, Brit Tørud, Simon Weli, Mona Cecilie Gjessingnegative. 2.10 RNA Extraction and Gene Expression Analysis Total RNA from alevin heads was extracted on a MagNA Pure 96 instrument (Roche, Switzerland) with the MagNA Pure 96 Cellular RNA Large Volume Kit (Roche, Switzerland), using

(15) Antiviral and immunomodulatory effect of zapnometinib in animal models and hospitalized COVID-19 patientsFrontiers in ImmunologySeptember 22, 2025Yvonne Füll, Lara M. Schüssele, Hazem Hamza, Helen Hoffmann, Martin Bauer, Stephan Stenglein, Oliver Pötz, Andreas Steinhilber, Viktoria Anselm, Mark W. Delany, et al.homogenized tissue samples was determined using an RT-qPCR method. Briefly, RNA was isolated with a Roche MagNA Pure 96 instrument using a MagNA Pure 96 DNA and Viral NA Small Volume Kit, and a TaqMan-based RT-qPCR assay was performed

(16) New mouse model based on adenocarcinoma 4T1 cells expressing HPV16 E6 and E7 applied to assess the efficacy of therapeutic and prophylactic E6/E7-based HPV16 vaccinesInfect Agent CancerJuly 26, 2025Juris Jansons, Daria Avdoshina, Alesja Dudorova, Elena Royo Rubio, Liba Sokolovska, Dmitry Perminov, Ilze Lindenberga, Hannes Nicolai, Svetlana Gebrila, Sona Chowdhury, et al.cells and tissues DNA was isolated from murine cells using the MagNA Pure 96 DNA Large Volume Kit by MagNA Pure 96 Instrument (both Roche, Basel, Switzerland). DNA from tumors and organs of mice preserved in FFPE blocks was isolated

(17) Severe pathological and transcriptional changes in haematopoietic organs of salmon suffering from salmon gill poxvirus diseaseBMC Vet ResJuly 16, 2025Ottavia Benedicenti, Ole Bendik Dale, Maria K. Dahle, Mona C. Gjessingspleen samples, respectively, with the MagNA Pure 96 Cellular RNA Large Volume Kit (Roche) and the MagNA Pure 96 Instrument (Roche). Sample quality was checked using the Thermo Scientific™ Multiskan Sky Microplate Spectrophotometer

(18) Pharmacokinetic Variability of Amlodipine Serum Concentration and Effect on Blood Pressure in Patients Treated for HypertensionPharmacol Res PerspectJuly 5, 2025Stine Rognstad, Camilla L. Søraas, Cathrine Brunborg, Lene V. Halvorsen, Karl Marius Brobak, Eirik Olsen, Ola U. Bergland, Arleen Aune, Silja S. Tuv, Anja Camilla Svarstad, et al.as obesity [27]. 2.5 Cytochrome P450 Testing Genomic DNA from EDTA whole blood was extracted on a Magna Pure 96 instrument (Roche, Oslo, Norway) at the Department of Medical Biochemistry and Pharmacology, OUH. The MassARRAY

(19) Clinical evaluation of two commercial PCR kits for the detection of nonviral sexually transmitted infectionsJ Med MicrobiolJuly 3, 2025Alexandre Gaudin, Nadège Hénin, Marie Gardette, Cécile Bébéar, Sabine Pereyreextracted from 200 µl clinical samples using the MagNA Pure 96 DNA and viral NA small-volume kit and the MagNA Pure 96 instrument (Roche Diagnostics) yielding a DNA extract of 100 µl (Fig. 1). The BK provides one internal control

(20) Development and verification of a novel tiling PCR method for long-range HIV-1 sequencing in a diagnostic settingSci RepJuly 1, 2025Bethany A. Horsburgh, Arunasingam Abayasingam, Frances Jenkins, Hui Li, Charles S. P. Foster, Andrew Lloyd, Lachlan Coin, William Rawlinson, Anthony D. Kelleher, Sebastiaan van Hal, et al.high-throughput extraction of RNA from samples prior to tiling PCR verification and benchmarking, the Roche MagNA Pure 96 Instrument was used. The DNA and Viral NA small volume kit (Roche #06543588001) and the pathogen universal 200

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