Magnetic separation may have seen its first use in biological applications as early as the 1970s. The technique, which uses natural or induced magnetic properties, relies on the use of magnetic beads. These spherical particles contain an iron core onto which various substances can be coated with various ligands with binding affinities, such as streptavidin, binding proteins, and antibodies. Magnetic separation can thus be used to purify or isolate biological compounds from a more complex mixture. This includes cleaning up nucleic acids in preparation for sequencing, purifying proteins and antibodies from cell lysates, and isolating specific cell types from blood and other media. It has also previously been used in the diagnostic detection of bacteria and viruses from the blood. This process offers advantages, such as minimal sample contact, low cost, and biologically non-invasive. Browse our catalog of magnetic separation tools listed by various suppliers.
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From 4D proteomics to artificial intelligence
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Set up a live demo with a Bio-Rad Imaging Specialist - Request a DemoUse the ChemiDoc MP Imaging System for flexible, high-sensitivity multiplex fluorescent and chemiluminescence western blot detection, imaging gels, analysis and documentation. This ...
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Light sheet microscopy allows for fast imaging of large 3D biological samples, like whole rodent organs, embryos or larvae. Compared to other current fluorescence microscopy techniques only a single plane of a labeled sample is illuminated ...
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My goal was to isolate CD14-positive cells (using positive or negative isolation) and mature them over three days into activated dendritic cells.
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The magnetic stand 96 is a paramagnetic bead precipitation used during preparation of DNA libraries for whole genome sequencing by Illumina. It is ideal for increasing throughput using samples in 96 well microplate. Separation is as quick as 30 ...
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