Caspase-Glo 3/7 Assay from Promega

Product Specs
ItemCaspase-Glo 3/7 Assay
CompanyPromega
Price Supplier Page View Company Product Page
Catalog NumberG8092
TargetCaspase 3 / Caspase 7
Quantity100ml
MethodLuminescent

Add to Compare List

Promega

2800 Woods Hollow Rd

Madison, WI 53711

United States

Phone: Tel: +1 (608) 274-4330
Fax: +1 (608) 277-2516

Email: custserv@promega.com
techserv@promega.com

Company Profile

Website: http://www.promega.com

(1) 30-hydroxygambogic acid activates overlapping and independent apoptotic pathways in HPV positive and HPV negative oral cancer cellsTumour Virus ResearchJune 1, 2026Danelle Grubbs, Sonia Whang, Valeria Rodarte, Briza Martinez, Valeri Filippov, John Chen, Jaqueline Coats, Julia Unternaehrer, Isaac Kremsky, Brigitte Vazquez, et al.analysis was performed as described [7]. 2.6 Caspase 3/7 Glo assay The Caspase 3/7 Glo Assay (Promega, G8091) was carried out according to the manufacturer's protocol. Each of the cell lines was assayed in duplicate

(2) Disruption of macrophage cell volume drives inflammatory responses and type I interferon signalingJ Cell BiolJune 1, 2026James R. Cook, Tara A. Gleeson, Sara Gago, Stuart M. Allan, Kevin N. Couper, Catherine B. Lawrence, David Brough, Jack P. Greena MTT assay kit (ab211091; Abcam), an LDH release kit (G1780; Promega), and a Caspase-Glo 3/7 kit (G8090; Promega) according to the manufacturer’s instructions. For MTT and LDH, 0.1 × 106 BMDMs were incubated

(3) Ferroptosis and Wnt/β-Catenin Signaling Triggered by Environmentally Relevant Nanoscale Polypropylene Plastics in Human Intestinal ModelsACS Environmental AuMay 20, 2026Sadman Sakib, Maohui Chen, Stephanie Skerrett, Daniel Prezgot, Magda Vandenberg, Adrian F. Pegoraro, Zygmunt J. Jakubek, Zeina Maan, Shan ZouMeasurements HSIOs and HIEC-6 cells were treated as described earlier. The Caspase-Glo 3/7 Assay System (G8090, Promega) was used to measure Caspase 3 and 7 activity for both organoids and monocultures. The Caspase Glo 1 Inflammasome assay

(4) A human iPSC-derived sensory neuron platform for high-throughput discovery of neuroprotectants against chemotherapy-induced peripheral neuropathyCell Rep MedMay 19, 2026Veselina Petrova, Caitlin E. Mills, Clemens Hug, Aysel Cetinkaya-Fisgin, Jennifer Splaine, Sepideh Fouladzadeh, Sara Hakim, Rasheen Powell, Shannon Zhen, Mirra Chung, et al.glo assay A caspase assay was performed using the Caspase-Glo 3/7 Assay System (Promega, cat. no. G8090) following the manufacturer’s instructions. Cells were treated with experimental compounds for 4 days

(5) Discovery, development, and characterization of SPY002 and SPY072, two novel extended half-life monoclonal antibodies targeting TL1A: in vitro properties, in vivo pharmacology, pharmacokinetics, and preclinical safetyMAbsMay 10, 2026Matthew Siegel, Eric Zhu, Daniel Rios, Byong H. Kang, Justin McNally, Michael Kennedy, Kinjal Hew, Preeyam Patel, Olivia Ballew, David H. Giles, et al.added to the wells. The plate was incubated at 37°C for 6 hours. Caspase-Glo® 3/7 reagent (Promega; G8092) was added at 50 μL/well, mixed using a plate shaker for 1 minute and then incubated for 30 minutes

(6) Novel N-chloroacetyl-2-pyrazoline analogs with 2-naphthyl and ferrocenyl groups: targeting histamine receptor H1 to overcome colorectal cancer drug resistanceCancer Drug ResistanceApril 30, 2026Dileepkumar Veeragoni, Hindole Ghosh, Affan Ansari, Sangita Bhattacharyya, Ahraar Azaz, Ojaswitha Ommi, Obdulia Covarrubias-Zambrano, Leonhard H. F. Köhler, Justus F. Ködel, Ameer Hamza, et al.1% concentration) to the control group. After 48 h of incubation, Caspase-Glo® 3/7 reagent (Promega, G8090) was added as per the manufacturer’s instructions. Following an additional hour of incubation, luminescent

(7) CSPG4 Mediates Inflammatory, Cell Death, and Senescence Responses in Enteric Glia Exposed to Clostridioides difficile ToxinsFASEB JApril 30, 2026Francisco M. S. Marques, Deiziane V. S. Costa, Conceição S. M. Rebouças, Gerly A. C. Brito, Cirle A. Warren, Renata F. C. Leitãomedium). 2.8 Caspase‐3/7 Activity Caspase‐3/7 activity was measured using the Caspase‐Glo 3/7 Assay (Promega, G8090), according to the manufacturer's instructions and as previously described [21]. Briefly, enteric glial cells

(8) New Insights into the Development of Papillary Thyroid Cancer: The Roles of miR-1179 and ELF3CellsApril 29, 2026Nicolas Henry, Nisrine Bahassou, Frédérick Libert, Geneviève Dom, Carine Maenhautand analyzed by flow cytometry. Caspase-3/7 activity was quantified using the Caspase-Glo® 3/7 assay (G8090, Promega). For this assay, 5 × 103 cells were seeded in 96-well plates 3 days after transfection to

(9) Isoform-specific cofactor recruitment through the intrinsically disordered N-terminus of p63 underlies differential transcriptional activitiesbioRxivApril 26, 2026Marina F. Nogueira, Michael J. Moore, Aparna R. Biswas, Michael P. Meers, Sidharth V. Puramdetermine base line levels of caspase-3/7 activation with the Caspase-Glo 3/7 Assay System (Promega, G8092). At the appropriate time intervals following dox induction (12 hours, 24 hours, etc.), we used the

(10) Activity of Didesmethylrocaglamide in High Grade Serous Ovarian Cancer Using Preclinical In Vitro and In Vivo ModelsJournal of Natural ProductsApril 24, 2026Elizabeth N. Kaweesa, Nicole Benson, Tyler A. Wilson, Ermias Mekuria Addo, Jane Miglo, Jaqueline M. Bazioli, Daniel D. Lantvit, Garima Agarwal, A. Douglas Kinghorn, James R. Fuchs, et al.and -7 activities were measured using a luminescence-based Caspase-Glo® 3/7 3/7 assay kit (Promega ;#G8091). The Caspase-Glo® 3/7 reagent, which also serves to lyse the cells, was added directly to each well

(11) Cryptocaryone Exhibits ROS/MAPK-Dependent Antiproliferative and Apoptosis-Inducing Effects on Triple-Negative Breast Cancer Cells and Proof-of-Concept Breast Cancer Mouse ModelDrug Dev ResApril 19, 2026Ya-Ting Chuang, Wangta Liu, Tsu-Ming Chien, Ammad Ahmad Farooqi, Hsun-Shuo Chang, Jun-Ping Shiau, Hsueh-Wei Chang(Chuang et al. 2025). For luminescence assays, caspase‐Glo 3/7 and caspase‐Glo 8 luminescence kits (#G8090 and #G8201) (Promega) were used to detect their activations as described (Chuang et al. 2025) and analyzed

(12) CSPG4 Mediates Inflammatory, Cell Death, and Senescence Responses in Enteric Glia Exposed to Clostridioides difficile ToxinsFASEB JApril 18, 2026Francisco M. S. Marques, Deiziane V. S. Costa, Conceição S. M. Rebouças, Gerly A. C. Brito, Cirle A. Warren, Renata F. C. Leitãomedium). 2.8 Caspase‐3/7 Activity Caspase‐3/7 activity was measured using the Caspase‐Glo 3/7 Assay (Promega, G8090), according to the manufacturer's instructions and as previously described [21]. Briefly, enteric glial cells

(13) RUVBL1 and RUVBL2 are druggable MYC effector regulators in neuroblastoma cellsiScienceApril 17, 2026Joachim Tetteh Siaw, Arne Claeys, Wei-Yun Lai, Marcus Borenäs, Elien Hilgert, Sarah-Lee Bekaert, Ellen Sanders, Irem Kaya, Jo Van Dorpe, Frank Speleman, et al.,ThermoFisher Scientific,Cat# 13778150 StemPro Accutase,Gibco,Cat# A11105-01 Caspase-Glo® 3/7 Assay kit,Promega,Cat# G8090 ,, Critical commercial assays,Critical commercial assays,Critical commercial assays ,, Cutana pA/G-MNase,Epicypher,Cat#

(14) RHOV is a Detachment-Responsive Rho GTPase Necessary for Ovarian Cancer Peritoneal MetastasisCancer ResApril 16, 2026Amal T. Elhaw, Priscilla W. Tang, Ya-Yun Cheng, Shriya Kamlapurkar, Zaineb Javed, Sarah Al-Saad, Sierra R. White, Ahmed Emam Abdelnaby, Hannah Khan, Alex Seok Choi, et al.in attached conditions: Caspase activity was evaluated using the Caspase-Glo 3/7 reagent (Promega, G8090). Cells were seeded in 96-well tissue culture treated dishes at 1000 cells/well for SKOV3 cells and

(15) RHOV is a Detachment-Responsive Rho GTPase Necessary for Ovarian Cancer Peritoneal MetastasisCancer ResApril 16, 2026Amal T. Elhaw, Priscilla W. Tang, Ya-Yun Cheng, Shriya Kamlapurkar, Zaineb Javed, Sarah Al-Saad, Sierra R. White, Ahmed Emam Abdelnaby, Hannah Khan, Alex Seok Choi, et al.in attached conditions: Caspase activity was evaluated using the Caspase-Glo 3/7 reagent (Promega, G8090). Cells were seeded in 96-well tissue culture treated dishes at 1000 cells/well for SKOV3 cells and

(16) Synthetic lethality of decitabine plus ATR inhibition for TP53-mutated AML∗Blood AdvancesApril 14, 2026Jeremy T. Baeten, Sumedha Agashe, Imene Tabet, Jack T. Wooldridge, Amber Carter, Jamie N. Butler, Christopher A. Miller, Nichole M Helton, Annabel Quinet, Kimberly B. Johansson, et al.were subjected to the CellTiter-Glo (CTG) 2.0 assay (#G9241; Promega) and the Caspase-Glo 3/7 assay (#G8091; Promega) as described previously.29 Briefly, cells were seeded at 30 000 cells per well in a round-bottom

(17) Protocol for rapid allelic discrimination qPCR genotyping of the Winnie mouse modelSTAR ProtocApril 11, 2026Behzad Mansoori, Chengyu Liangassays ,, PreciGene™ Quick Extraction Kit,BioPioneer Inc.,#MAQ-1 TaqMan Gene Expression Master Mix,Promega,G8090 ,, Others,Others,Others ,, PCR Thermal Cycler,BioRad,C1000 Real-Time PCR System,BioRad,CFX Opus CFX Maestro Software

(18) Discovery of a First-in-Class Murine Double Minute 2-Recruiting Positive Transcription Elongation Factor B PROTAC Degrader With Selective Antitumor ActivityMedComm (2020)April 9, 2026Xian Guan, Long Xie, Hanjun Guo, Lin Ma, Jiawei Zhou, Lisong Luo, Hao Yang, Yuanfang Wu, Jiangyu Liu, Yue Wang, et al.monitored by measuring Caspase‐3/7 activity using the Caspase‐Glo 3/7 Assay (Promega, Madison, WI, USA; G8091). Cells were seeded in white‐walled 96‐well plates at 10,000 cells per well. After 24‐h compound treatment,

(19) Targeting ST18-mediated pathomechanism in pemphigus vulgaris through voltage-dependent anion channel inhibitionSkin Health and DiseaseMarch 31, 2026Sari Assaf, Ofer Sarig, Rawaa Ishtewy, Yazeed Zoabi, Yarden Feller, Kiril Malovitski, Janan Mohamad, Shir Bergson, Carmel Bilu, Varda Shoshan-Barmatz, et al.Institutes of Health, Bethesda, MD, USA). Caspase 3/7 assay The Caspase-Glo® 3/7 Assay System kit (G8090; Promega, Madison, WI, USA) was conducted according to the manufacturer’s instructions. Briefly, cells

(20) Apoptotic Effects of Agapanthus africanus Extracts and Identification of Volatile Compounds from the n-Butanol FractionMoleculesMarch 24, 2026Makgwale S. Mphahlele, Kingsley C. Mbara, Daniel M. Tswaledi, Raymond T. Makola, Clemence Tarirai, Jeremia L. Shaicaspase-Glo® 3/7 activity, caspase-Glo® 3/7 assay system (Promega (Madison, WI, USA), catalog number: G8090) was used, an equal volume of Caspase-Glo® 3/7 reagent was added to each well and mixed gently. The

Write a Review

(1)

2/3/2017Great Easy Assay To Measure Caspase Activation With Plate Reader Tara VanderweydeThis is a luminescent assay that measures caspase-3 and -7 activities in purified enzyme preparations or cultures of adherent or suspension cells. The assay provides a proluminescent caspase-3/7 ... Read Review

Caspase-Glo® 3/7 Assay System From Promega
The Promega Caspase-Glo® 3/7 Assay System is a homogeneous luminescent method used to measure ... Read More