Human Chitinase 3-like 1/YKL-40 Quantikine ELISA Kit DC3L10 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemHuman Chitinase 3-like 1/YKL-40 Quantikine ELISA Kit
CompanyR&D Systems, a Bio-Techne Brand
Price $680.00Supplier Page View Company Product Page
Catalog NumberDC3L10
Quantity1 Kit
ApplicationsELISA
Detection Range62.50 - 4000 pg/mL
ReactivityHuman
Sample TypeCell Culture Supernates (50 uL), Serum (10 uL), EDTA Plasma (10 uL), Heparin Plasma (10 uL), Urine (50 uL)
Sensitivity8.15 pg/mL
Detection TargetChitinase 3-like 1/YKL-40
Assay Time4.5 hours
StorageStore the unopened product at 2 - 8 °C. Do not use past expiration date
NCBI Full Gene Namechitinase 3 like 1
NCBI Gene AliasesASRT7, CGP-39, GP-39, GP39, HC-gp39, HCGP-3P, YK-40, YKL-40, YKL40, YYL-40, hCGP-39

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Systemic–airway eosinophil discordance and sputum mediator profiling in severe asthma treated with biologics: a retrospective cohort studyBMC Pulmonary MedicineApril 13, 2026Moe Tanaka, Toshiyuki Koya, Wakana Uji, Hiroki Koda, Masahiro Endo, Kyoichiro Oshima, Haruka Sofuku, Takahiro Matsuda, Shun Naramoto, Hiroshi Ueno, et al.Concentrations of ECP (SK00128-06, Aviscera Bioscience), tryptase (SEB070Hu, Cloud-Clone), YKL-40 (DC3L10, R&D Systems), IL-6 (D6050B, R&D Systems), and IL-18 (BMS267-2, Thermo Fisher Scientific) in sputum

(2) Serum Chitinase 3-like-1 (CHI3L1) Has Good Correlation with Fecal Calprotectin Levels in Pregnant IBD PatientsJ Pers MedMarch 3, 2026Hagai Schweistein, Rachel Gingold-Belfer, Adi Rave, Ahinoam Glusman-Bendersky, Hadar Amir-Barak, Jacob E. Ollech, Ariella Bar-Gil Shitritmanufacturer’s instructions, serum CHI3L1 levels were measured using an ELISA assay kit (Quantikine ELISA #DC3L10, R&D Systems, Minneapolis, MN, USA). Results were reported in ng/mL. Assay calibration was validated

(3) CHI3L1 Expression in Chordoma: Implications for Immunotherapeutic InterventionCellsFebruary 22, 2026Beatrice Campilan, Christian Godinez, Jonathan Arditi, Jessica Ding, Kaylee Gallagher, Andrew Fogarty, Christian Schroeder, Madison J. Michles, Weston de Lomba, Joselynn Wallace, et al.measurements were obtained using the Human Chitinase 3-like 1/YKL-40 Quantikine ELISA Kit (R&D Systems Cat. DC3L10, Minneapolis, MN, USA). Supernatant was collected from JHC7 (n = 6), U-CH12 (n = 9), U-CH1 (n = 9),

(4) Kidney Injury Urine Biomarker Normal Ranges in ChildrenKidney International ReportsFebruary 4, 2026Hannah Weber, Katharina Schermuly, Anna Tschirner, Ineke Böckmann, Veronika Esslinger, Helene Tietze, Ulrich Baumann, Anibh M. Das, Nele Kanzelmeyer, Jens Drube, et al.Catalog No. DY1118, sensitivity 31.2 pg/ml), CHI3L1 (Quantikine ELISA, R&D system; MN, Catalog No. DC3L10; sensitivity 8.15 pg/ml), MCP-1 (Quantikine ELISA, R&D system;MN, Catalog No. DCP00; sensitivity 10

(5) Characterization of a pathogenic subpopulation of human glioma associated macrophages linked to glioma progressionCancer CellJanuary 12, 2026Kenny Kwok Hei Hei Yu, Zaki Abou-Mrad, Kristof Törkenczy, Isabell Schulze, Jennifer Gantchev, Gerard Baquer, Kelsey Hopland, Evan D. Bander, Umberto Tosi, Cameron Brennan, et al.,Novus Biologicals,cat# NBP2-75354 Human Chitinase 3-like 1/YKL-40 Quantikine ELISA Kit Deposited data,R&D Systems,cat# DC3L10 Human Glioma scRNA-seq data,Current Study,GEO database: GSE275225 Human Normal Brain scRNA-seq,Current

(6) Synolitic Graph Neural Networks of High-Dimensional Proteomic Data Enhance Early Detection of Ovarian CancerCancers (Basel)December 12, 2025Alexey Zaikin, Ivan Sviridov, Janna G. Oganezova, Usha Menon, Aleksandra Gentry-Maharaj, John F. Timms, Oleg BlyussSwitzerland; Elecsys CA 125 II; 1:1; 4%), CHI3L1 Quantikine ELISA Kit (R&D Systems, Minneapolis, MN, USA; DC3L10; 1:50; 14%), DNAH17 (human) ELISA Kit (EIAab, Wuhan, China; E5886h; 1:5; 17%), FSTL1 ELISA Kit (USCN,

(7) Plasma CHI3L1 associates with brain volume loss and glial activation in multiple sclerosisJ Neurol Neurosurg PsychiatryOctober 15, 2025Venla Ahola, Maija Saraste, Marjo Nylund, Markus Matilainen, Amelie Luoma, Anna Vuorimaa, Jussi Lehto, Sini Laaksonen, Eeva-Christine Brockmann, Jens Kuhle, et al.sandwich enzyme immunoassay technique (ELISA). Human Chitinase 3-like 1/YKL-40 Quantikine ELISA-Kit (DC3L10, R&D Systems) was used following manufacturer’s instructions with recommended dilution 1:50. Optical

(8) Identification and evaluation of potential microRNA markers for diagnostics in neurodegenerative diseases and correlation with other biochemical markersPLoS OneOctober 10, 2025Richard Novobilský, Pavlína Kušnierová, Dominik Štěpán, Petra Bártová, David Stejskal, Michal BarEuroimmun) and Chitinase-3-like 1 (CHI3L1) by Quantikine ELISA Human Chitinase-3-like 1 Immunoassay (REF DC3L10, R&D Systems, USA&Canada). The detection limits were 0.4 ng/L for S NfL, 33 ng/L for CSF NfL, 28 ng/L

(9) Potential of biomarker-based enrichment strategies to identify critically ill patients for emerging cell death interventionsCell Death & DifferentiationJuly 19, 2025Cyril Willemart, Ruth Seurinck, Tom Stroobants, Samya Van Coillie, Jorien De Loor, Sze Men Choi, Ria Roelandt, Mohan Rajapurkar, Symen Ligthart, Philippe G. Jorens, et al.#1421253) to prevent iron contamination. The concentration of CHI3L1 was measured with a sandwich ELISA (DC3L10, R&D Systems, Minneapolis, MN, USA) in both serum and urine using dilutions as described in the initial

(10) Proteomic analysis of Down syndrome cerebrospinal fluid compared to late-onset and autosomal dominant Alzheimer´s diseaseNature communicationsJuly 1, 2025Montoliu-Gaya L, Bian S, Dammer EB, Alcolea D, Sauer M, Martá-Ariza M, Ashton NJ, Belbin O, Fuchs J, Watson CM, et al.previously described90. CSF YLK-40 levels were measured by YKL-40 human chitinase-3-like 1 immunoassay, DC3L10, R&D Systems, USA (ELISA) using a dilution of 1:100 and by YKL-40 MicroVue, Quidel, San Diego (USA). CSF

(11) Chitinase-3-Like 1 Protein (CHI3L1) Levels in Patients With Cognitive Deficits and Movement Disorders: Comparison With Other BiomarkersBrain BehavJune 10, 2025R. Novobilský, P. Bártová, D. Stejskal, A. Kondé, M. Bar, P. KušnierováMethods The concentrations of S CHI3L1 were determined by ELISA (Human Chitinase 3‐like 1 Immunoassay, REF DC3L10, RUO, R&D Systems, Inc.). The kit manufacturer stated that the detection limit was 3.55 ng/L. All samples

(12) Temporal dynamics of the interstitial fluid proteome in human skeletal muscle following exhaustive exerciseScience advancesJanuary 31, 2025Stocks B, Quesada JP, Mozzicato AM, Jacob C, Jensen S, MacGregor KA, Bangsbo J, Zierath JR, Hostrup M, Deshmukh AS.difference Arterial and venous plasma samples were thawed and the concentrations of MB (ab171580, abcam), CH3IL1 (DC3L10, R&D Systems), LCN2 (DLCN20, R&D Systems), LL-37 (HK321, HycultBiotech), and MMP8 (DMP800B, R&D Systems)

(13) Neurofilament heavy chain and chitinase 3-like 1 as markers for monitoring therapeutic response in multiple sclerosisMultiple sclerosis and related disordersNovember 1, 2024Kusnierova P, Revendova KZ, Karasova K, Zeman D, Bunganic R, Hradilek P, Volny O, Ganesh A, Kovacova I, Stejskal D.

(14) Evaluating serum periostin and YKL-40 as biomarkers for airway remodeling and hyperresponsiveness in pediatric asthma☆World Allergy Organization JournalNovember 1, 2024Su Ji Kim, Youn Joo Choi, Man Yong Han, Il Tae Hwang, Hey-Sung Baekwere also measured by ELISA using the Human Chitinase 3-like 1 Quantikine ELISA Kit (catalog number DC3L10; R&D Systems, Inc., Minneapolis, MN, USA). Experiments were performed in accordance with to the manufacturer's

(15) Early Fever in Allogeneic Stem Cell Transplantation: Are Presepsin and YKL-40 Valuable Diagnostic Tools?Journal of clinical medicineOctober 8, 2024Babel J, Košuta I, Vujaklija Brajković A, Lončar Vrančić A, Premužić V, Rogić D, Duraković N.Switzerland). YKL-40 concentration was determined using a Human Chitinase 3-like 1 Immunoassay ELISA kit (ref. DC3L10 R&D Systems Inc., Minneapolis, MN, USA). The manufacturer-claimed linearity is 3.55–4000 pg/mL. The

(16) YKL40/Integrin β4 Axis Induced by the Interaction between Cancer Cells and Tumor-Associated Macrophages Is Involved in the Progression of High-Grade Serous Ovarian CarcinomaInternational journal of molecular sciencesOctober 1, 2024Yamanaka K, Koma YI, Urakami S, Takahashi R, Nagamata S, Omori M, Torigoe R, Yokoo H, Nakanishi T, Ishihara N, et al.

(17) Neuroinflammation, cerebrovascular dysfunction and diurnal cortisol biomarkers in a memory clinic cohort: Findings from the Co-STAR studyTranslational PsychiatrySeptember 9, 2024Makrina Daniilidou, Jasper Holleman, Göran Hagman, Ingemar Kåreholt, Malin Aspö, Ann Brinkmalm, Henrik Zetterberg, Kaj Blennow, Alina Solomon, Miia Kivipelto, et al.chitinase 3-like 1 (YKL-40/CHI3L1) was quantified with a commercially available sandwich ELISA kit (DC3L10, R&D Systems, USA), following the manufacturer’s instructions with a sample dilution 1:150. Samples

(18) Alzheimer's disease CSF biomarkers correlate with early pathology and alterations in neuronal and glial gene expressionAlzheimer's & DementiaAugust 27, 2024Ali S. Ropri, Tiffany G. Lam, Vrinda Kalia, Heather M. Buchanan, Anne Marie W. Bartosch, Elliot H. H. Youth, Harrison Xiao, Sophie K. Ross, Anu Jain, Jayanta K. Chakrabarty, et al.the manufacturers’ instructions. Levels of NPTXR (#ELH‐NPTXR; Ray Biotech, GA, USA), and YKL‐40 (# DC3L10; R&D systems, MN, USA), were assessed using a 1:10 and 1:100 dilution, respectively. 2.4 Metabolomics

(19) Multimodal single-cell analyses reveal mechanisms of perianal fistula in diverse patients with Crohn’s diseaseMedAugust 9, 2024Rachel M. Levantovsky, Christopher Tastad, Jiayu Zhang, Kyle Gettler, Ksenija Sabic, Robert Werner, Colleen Chasteau, Ujunwa Korie, Diana Paguay, Michelle Bao, et al.concentration of CHI3L1 was detected using the Human Chitinase 3-like 1 Quantikine ELISA Kit (R&D Systems, DC3L10) according to manufacturer’s instructions. Optical density absorbance readings were obtained using The

(20) Alzheimer's disease CSF biomarkers correlate with early pathology and alterations in neuronal and glial gene expressionmedRxiv : the preprint server for health sciencesJune 13, 2024Ropri AS, Lam TG, Kalia V, Buchanan HM, Bartosch AMW, Youth EHH, Xiao H, Ross SK, Jain A, Chakrabarty JK, et al.

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Human Chitinase 3-like 1/YKL-40 Quantikine ELISA Kit

Chitinase 3-like 1 ELISA

Chitinase 3-like 1 ELISA

Chitinase 3-like 1 ELISA

Human Chitinase 3-like 1/YKL-40 Quantikine ELISA Kit from R&D Systems, a Bio-Techne Brand

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R&D Systems, a Bio-Techne Brand

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Human Chitinase 3-like 1/YKL-40 Quantikine ELISA Kit from R&D Systems, a Bio-Techne Brand

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