Fig 1: The effect of Lbz (6.25 and 12.5 mg/kg) and prednisone on colonic levels of ZO-1, claudin-1, MALK, and occludin. (A) ZO-1 level; (B) claudin-1 level; (C) MLCK level; (D) occludin immune figure; (E) bar graph showing the % expression of occludin. Expression in the cytoplasm of the cells (thick arrows) and the lamina propria (thin arrows). Data are expressed as mean ± SD (n = 4). Lbz: Lobenzarit; Dss: dextran sulphate sodium; MALK: ATP-hydrolyzing subunit of the maltose/trehalose transport system; ZO-1: Zonula Occludens-1. Statistically significant: * p < 0.05, compared to the control group; # p < 0.05, compared to the Dss group; $ p < 0.05 compared to the prednisone + Dss group; % p < 0.05 compared to the Lbz 6.25 + Dss group. Analyses were performed using one-way ANOVA followed by the Tukey–Kramer multiple-comparisons post hoc test.
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