Fig 1: CSF and serum KNG protein level of encephalitis patients and controls. (A) The level of KNG in CSF of encephalitis and control patients. (B) The level of KNG in serum of encephalitis and control patients. (C) The correlation of serum and CSF KNG levels in encephalitis patients. (D) The correlation of serum and CSF KNG levels in control patients. **p < 0.01.
Fig 2: Correlation between acute symptomatic seizure and KNG protein level in post-acute phase CSF/ serum. (A) The level of KNG in CSF of control and encephalitis patients with and without acute phase symptomatic seizure. (B) The level of KNG in serum of control and encephalitis patients with and without acute phase symptomatic seizure. *p < 0.05.
Fig 3: Correlation between post-acute phase CSF and serum KNG protein level and symptomatic epilepsy in 2 years. (A) The level of KNG in CSF of control and encephalitis patients with and without symptomatic epilepsy. (B) The level of KNG in serum of control and encephalitis patients with and without symptomatic epilepsy. *p < 0.05, **p < 0.01.
Fig 4: Verification of the upregulation of KNG in CSF during early epileptogenesis. (A) The level of KNG in CSF using ELISA. (B) The level of KNG in the hippocampus using Western blotting. (C) The level of KNG in serum using ELISA. *p < 0.05, **p < 0.01, ***p < 0.001.
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