Fig 1: Relationship between miR-3663-3p expression and inflammation in sepsis. Correlation analysis of (A) miR-3663-3p expression with the serum levels of IL-6, IL-21, CXCL8 and MCP-1 and TDAG8 and TLR4 mRNA. Correlation analysis of (B) TLR4 and (C) TDGA8 mRNA expression with the serum contents of IL-6, IL-21, CXCL8 and MCP-1. (D) ROC curve analysis of miR-3663-3p expression, total serum IL-6, IL-21, CXCL8 and MCP-1 concentration and TDAG8 and TLR4 mRNA expression in patients with sepsis. (E) Expression levels of miR-3663-3p in human peripheral blood samples detected by reverse transcription-quantitative PCR. **P<0.01 vs. healthy controls. miR, microRNA; CXCL8, C-X-C motif chemokine ligand-8; MCP-1, monocyte chemoattractant protein-1; TDAG8, T-cell death-associated gene 8; TLR4, toll-like receptor 4; ROC, receiver operating characteristic; NC, normal control.
Fig 2: Levels of serum cytokines/chemokines. ELISA determination of serum (A) IL-6, (B) IL-21, (C) CXCL8 and (D) MCP-1 content in patients with sepsis and healthy controls. **P<0.01 and ***P<0.001 vs. healthy controls. CXCL8, C-X-C motif chemokine ligand-8; MCP-1, monocyte chemoattractant protein-1; NC, normal healthy controls.
Supplier Page from CUSABIO Technology LLC for Human Interleukin 21,IL-21 ELISA Kit