Mouse IL-6R alpha DuoSet ELISA DY1830 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemMouse IL-6R alpha DuoSet ELISA
CompanyR&D Systems, a Bio-Techne Brand
Price $890.00Supplier Page View Company Product Page
Catalog NumberDY1830
Quantity1 Kit (for 15 Plates)
ApplicationsELISA
Detection Range46.90 - 3000 pg/mL
ReactivityMouse
Detection TargetIL-6R alpha
StorageStore the unopened product at 2 - 8 °C. Do not use past expiration date
NCBI Full Gene Nameinterleukin 6 receptor, alpha
NCBI Gene AliasesCD126, IL-6R, IL-6R-alpha, IL-6RA, Il6r

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Treg-specific IL-6R signaling: a novel role in the regulation of the intestinal epitheliumAmerican Journal of Physiology-Gastrointestinal and Liver PhysiologyDecember 1, 2025Emily E. Klatt, Feda H. Hamdan, Isaiah Pérez, Hannah M. Smith, Kimberlee Kossick, Yaroslav Fedyshyn, Mary R. Sagstetter, David Chiang, Lucas C. S. Chini, Heidi M. Davidson, et al.analyzed for expression of sIL-6R using the Mouse IL-6R alpha Duoset ELISA Kit (Bio-Techne, catalog DY1830). Following completion of the manufacturer protocol, the ELISA plate was analyzed in a 96-well plate

(2) Zfp580 inactivation as a new therapeutic target to enhance recovery after stroke in miceJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and MetabolismAugust 1, 2023Hoffmann CJ, Kuffner MT, Koschützke L, Lorenz S, Lips J, Boehm-Sturm P, Mueller S, Koch SP, An J, Fekonja LS, et al.in cell culture supernatants, Il6 (R&D Systems, M6000B, Minneapolis, MN, USA) or sIl6r (R&D Systems, DY1830) were performed according to the manufacturer’s instructions. The binary Il6:Il6r complex was quantified

(3) In vivo immunomodulation of IL6 signaling in a murine multiple trauma modelImmunologic ResearchApril 1, 2023Tom Malysch, Jens Michael Reinhold, Christopher A. Becker, Katharina Schmidt-Bleek, Christian KleberThe sIL6-R serum levels were measured by ELISA in triplets (dilution 1:32; Mouse IL-6 R alpha DuoSet DY1830; R&D Systems). These samples (dilution 1:32) had previously been validated by spike and recovery test

(4) Interleukin 6 receptor is not directly involved in regulation of body weight in diet-induced obesity with and without physical exerciseFront Endocrinol (Lausanne)October 27, 2022Anna Rita Minafra, Alexandra Chadt, Puyan Rafii, Hadi Al-Hasani, Kristina Behnke, JÃ¼rgen Schellerserum To quantify mouse serum sIL-6R, the enzyme-linked immunosorbent assay (Mouse IL-6Ra DuoSet, cat. #DY1830, R&D Systems, Minneapolis, MN, USA) was used. Microtitre plates (Nunc maxi sorb, Sigma Aldrich, Munich,

(5) Cathepsin S provokes interleukin-6 (IL-6) trans-signaling through cleavage of the IL-6 receptor in vitroScientific reportsDecember 10, 2020Flynn CM, Garbers Y, Düsterhöft S, Wichert R, Lokau J, Lehmann CHK, Dudziak D, Schröder B, Becker-Pauly C, Rose-John S, et al.

(6) Functional Characterization of Colon-Cancer-Associated Variants in ADAM17 Affecting the Catalytic DomainBiomedicinesOctober 30, 2020Jan Philipp Dobert, Anne-Sophie Cabron, Philipp Arnold, Egor Pavlenko, Stefan Rose-John, Friederike Zunkemanufacturer’s instructions (mTNFα: #11560637 eBioscience, Frankfurt am Main, Germany; mIL-6R and mAREG: #DY1830 and #DY989, R and D Systems, Minneapolis, MN, USA). 2.9. Live Cell Surface ADAM17 Activity Assay First,

(7) Anti-interleukin-6 receptor antibody treatment ameliorates postoperative adhesion formationScientific reportsNovember 26, 2019Uyama N, Tsutsui H, Wu S, Yasuda K, Hatano E, Qin XY, Kojima S, Fujimoto J.IL-6 (M6000B, R&D Systems), TNF-α (MTA00B, R&D Systems), TGF-β1 (MB100B, R&D Systems), and sIL-6Rα (DY1830, R&D Systems), respectively. The abundance of IL-6 in human sera and ascites was measured by a human

(8) IL-6 exhibits both cis- and trans-signaling in osteocytes and osteoblasts, but only trans-signaling promotes bone formation and osteoclastogenesisThe Journal of biological chemistryMay 10, 2019McGregor NE, Murat M, Elango J, Poulton IJ, Walker EC, Crimeen-Irwin B, Ho PWM, Gooi JH, Martin TJ, Sims NA.

(9) miR-146a modulates autoreactive Th17 cell differentiation and regulates organ-specific autoimmunityThe Journal of clinical investigationOctober 2, 2017Li B, Wang X, Choi IY, Wang YC, Liu S, Pham AT, Moon H, Smith DJ, Rao DS, Boldin MP, et al.

(10) Intravitreal injection of anti-Interleukin (IL)-6 antibody attenuates experimental autoimmune uveitis in miceCytokineAugust 1, 2017Tode J, Richert E, Koinzer S, Klettner A, Pickhinke U, Garbers C, Rose-John S, Nölle B, Roider J.

(11) Interleukin‐6 receptor alpha blockade improves skin lesions in a murine model of systemic lupus erythematosusExperimental DermatologyApril 26, 2016Peter Birner et al.and Ribosomal P protein as previously described 10. Serum levels of sIL‐6R were determined by ELISA (DY1830, R&D Systems, Minneapolis, MN, USA). Urine albumin levels were investigated using a murine α‐Albumin

(12) The soluble interleukin-6 receptor is a mediator of hematopoietic and skeletal actions of parathyroid hormoneThe Journal of biological chemistryMarch 8, 2013Cho SW, Pirih FQ, Koh AJ, Michalski M, Eber MR, Ritchie K, Sinder B, Oh S, Al-Dujaili SA, Lee J, et al.

(13) Cutting edge: Inhibition of IL-6 trans-signaling protects from malaria-induced lethality in miceJournal of immunology (Baltimore, Md. : 1950)May 1, 2012Wunderlich CM, Delić D, Behnke K, Meryk A, Ströhle P, Chaurasia B, Al-Quraishy S, Wunderlich F, Brüning JC, Wunderlich FT.

(14) Leukocyte ADAM17 regulates acute pulmonary inflammationPloS oneJanuary 1, 2011Arndt PG, Strahan B, Wang Y, Long C, Horiuchi K, Walcheck B.

(15) Loss of CD4+ T cell IL-6R expression during inflammation underlines a role for IL-6 trans signaling in the local maintenance of Th17 cellsJournal of immunology (Baltimore, Md. : 1950)February 15, 2010Jones GW, McLoughlin RM, Hammond VJ, Parker CR, Williams JD, Malhotra R, Scheller J, Williams AS, Rose-John S, Topley N, et al.

(16) Essential roles of IL-6 trans-signaling in colonic epithelial cells, induced by the IL-6/soluble-IL-6 receptor derived from lamina propria macrophages, on the development of colitis-associated premalignant cancer in a murine modelJournal of immunology (Baltimore, Md. : 1950)February 1, 2010Matsumoto S, Hara T, Mitsuyama K, Yamamoto M, Tsuruta O, Sata M, Scheller J, Rose-John S, Kado S, Takada T.

(17) Direct B cell stimulation by dendritic cells in a mouse model of lupusArthritis and rheumatismJune 1, 2008Wan S, Zhou Z, Duan B, Morel L.

(18) Classic interleukin-6 receptor signaling and interleukin-6 trans-signaling differentially control angiotensin II-dependent hypertension, cardiac signal transducer and activator of transcription-3 activation, and vascular hypertrophy in vivoThe American journal of pathologyJuly 1, 2007Coles B, Fielding CA, Rose-John S, Scheller J, Jones SA, O'Donnell VB.

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IL-6R alpha ELISA

Mouse IL-6R alpha DuoSet ELISA

Mouse IL-6R alpha DuoSet ELISA from R&D Systems, a Bio-Techne Brand

R&D Systems, a Bio-Techne Brand

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Mouse IL-6R alpha DuoSet ELISA from R&D Systems, a Bio-Techne Brand

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