Fig 1: TACE/ADAM17 substrates in ACS and follow-up MACE. Levels of TACE/ADAM17 substrates TRANCE, LDLR, LAG-3 and ACE2 were significantly higher in CAD patients compared to controls. Levels of HB-EGF, Ep-CAM, TNFR1 were able to accurately classify ACS patients and levels of TNFR1 and TNFR2 associated with MACE upon follow-up. TACE inhibitor, TIMP3 mRNA levels were lower in CAD patients and tended to be lower in ACS compared to elective CAD patients.
Fig 2: TIMP3 mRNA expression levels is lower in CAD patients and tends to be lower in those admitted with ACS.
Supplier Page from Abcam for Human TIMP3 ELISA Kit (MIG-5)