Fig 1: BMSCs-exo reduced the apoptosis of skin flap. (A) TUNEL staining (red) of tissue sections of the three groups (scale bar, 50 μm); (B) Number of TUNEL positive cells, *** p < 0.001; (C) Western blot analysis of Bax and Bcl-2 expression in the three groups; (D) Quantitative analysis of the expression levels of Bax and Bcl-2, * p < 0.05 and * p < 0.01; (E,F) Evaluation of SOD activities and MDA contents of the three groups, ** p < 0.01; (G,H) Expression levels of TNF-a and IL-1β were measured by ELISA analysis, *** p < 0.001.