IL-28A/IFN-lambda 2 ELISA DY1587 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemIL-28A/IFN-lambda 2 ELISA
CompanyR&D Systems, a Bio-Techne Brand
Price $890.00Supplier Page View Company Product Page
Catalog NumberDY1587
NCBI Full Gene Nameinterferon lambda 2
NCBI Gene AliasesIFNL2a, IFNL3a, IL-28A, IL28A
StorageStore the unopened product at 2 - 8 °C. Do not use past expiration date
Assay Time4 hours 40 minutes (after plate preparation)
Detection TargetIL-28A/IFN-lambda 2
ReactivityHuman
Detection Range125.00 - 8000 pg/mL
ApplicationsELISA
Quantity1 Kit (for 15 Plates)

Specifications/Features

Available conjugates: Sizes Available: 1 Kit (for 15 Plates)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Basal IFNλ2/3 signaling is required for ISG expression and viral control in human intestinal epithelial cellsPLOS PathogensJanuary 12, 2026Yagmur Keser, Zehra Sena Bumin, Amelia Perez Valiente, Sorin O. Jacobs, Steeve Boulant, Megan L. Staniferdetection antibodies provided in the corresponding DuoSet ELISA kits (R&D Systems, Bio-Techne # DY7246, #DY1587, # DY5259). For each interferon, neutralization was performed individually. Capture and detection antibodies

(2) Reduced IFNL1 and/or IFNL2, but not IFNL3 is associated with worse outcome in patients with COVID-19Clinical and Experimental ImmunologyNovember 12, 2024Elena Woods, Adriana Mena, Sophie Sierpinska, Emily Carr, STTAR Bioresource, Richard Hagan, John Crowley, Colm Bergin, David Clark, Caroline Brophy, et al.EDTA plasma using the Duo Set ELISA kit according to manufacturer’s instructions (R&D Systems—DY7246, DY1587, DY5259, respectively). Each biological sample was assayed in duplicate. A standard curve was used for

(3) Restoration of dendritic cell homeostasis and Type I/Type III interferon levels in convalescent COVID-19 individualsBMC immunologyOctober 26, 2022Rajamanickam A, Kumar NP, Pandiaraj AN, Selvaraj N, Munisankar S, Renji RM, Venkatramani V, Murhekar M, Thangaraj JWV, Kumar MS, et al.

(4) Serum IL-28A/IFN-λ2 is linked to disease severity of COVID-19Scientific reportsMarch 31, 2022Fukuda Y, Homma T, Inoue H, Goto Y, Sato Y, Ikeda H, Onitsuka C, Sato H, Akimoto K, Ebato T, et al.

(5) Human Placental Trophoblasts Infected by Listeria monocytogenes Undergo a Pro-Inflammatory Switch Associated With Poor Pregnancy OutcomesFrontiers in ImmunologyJuly 23, 2021Lauren J. Johnson, Siavash Azari, Amy Webb, Xiaoli Zhang, Mikhail A. Gavrilin, Joanna M. Marshall, Kara Rood, Stephanie Seveau(Meso Scale Discovery). IFNL1, IFNL2, and IFNL3 ELISAs were performed using the human IL-29 (DY7246), IL-28A (DY1587), and IL-28B (DY5259) DuoSet ELISA kits (R&D Systems) per the manufacturer’s instructions. Colocalization

(6) Aggressive PDACs Show Hypomethylation of Repetitive Elements and the Execution of an Intrinsic IFN Program Linked to a Ductal Cell of OriginCancer discoveryMarch 1, 2021Espinet E, Gu Z, Imbusch CD, Giese NA, Büscher M, Safavi M, Weisenburger S, Klein C, Vogel V, Falcone M, et al.ELISA kit (EHIFNG, Invitrogen), Human IL-29/IFN-λ1 (DY7246, R&D Systems), and Human IL-28A/IFN-λ2 (DY1587, R&D Systems). Generation of knock-down cells STAT1 and MAVS knock-downs were generated with a miR-E

(7) Comparative Transcriptomic Analysis of Rhinovirus and Influenza Virus InfectionFrontiers in MicrobiologyJuly 21, 2020Thrimendra Kaushika Dissanayake et al.independent experiment. ELISA was done using Human DuoSet ELISA kits for IFN-λ1/λ2/λ3 (Catalog number DY7246, DY1587, DY5259) and CXCL10 (Catalog number DY266) (R&D Systems). Error bars represent SEM. Statistical significance

(8) Diminished circulating plasma and elevated lymph node culture supernatant levels of IL-10 family cytokines in tuberculous lymphadenitisCytokineNovember 1, 2018Kathamuthu GR, Kumar NP, Moideen K, Baskaran D, Hissar S, Shrinivasa BM, Sridhar R, Babu S.

(9) Kinetic Differences and Synergistic Antiviral Effects Between Type I and Type III Interferon Signaling Indicate Pathway IndependenceJournal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine ResearchSeptember 1, 2015Voigt EA, Yin J.in cell culture media using DuoSet ELISA development systems and the DuoSet ancillary reagent set (Nos. DY7246, DY1587, DY5259, and DY008; R&D Systems, Minneapolis, MN). IFN-a, IFN-b (diluted 1:2), and IFN-g were detected

(10) Mesenchymal stem cells are efficiently transduced with adenoviruses bearing type 35-derived fibers and the transduced cells with the IL-28A gene produces cytotoxicity to lung carcinoma cells co-culturedBMC cancerSeptember 25, 2014Suzuki T, Kawamura K, Li Q, Okamoto S, Tada Y, Tatsumi K, Shimada H, Hiroshima K, Yamaguchi N, Tagawa M.

(11) Hepatitis C virus NS3/4A protease blocks IL-28 productionEuropean journal of immunologySeptember 1, 2012Ding Q, Huang B, Lu J, Liu YJ, Zhong J.

(12) Activation of type III interferon genes by pathogenic bacteria in infected epithelial cells and mouse placentaPloS oneJanuary 1, 2012Bierne H, Travier L, Mahlakõiv T, Tailleux L, Subtil A, Lebreton A, Paliwal A, Gicquel B, Staeheli P, Lecuit M, et al.manufacturer’s instructions, with the following references: IFN-λ1/λ3 and IFN-λ2 (Duoset ELISA kit, DY1598B and DY1587, R&D Systems), IFN-β (VeriKine ELISAs, #41410-1A, PBL Biomedical Laboratories, Piscataway, NJ, USA)

(13) Type III interferons, IL-28 and IL-29, are increased in chronic HCV infection and induce myeloid dendritic cell-mediated FoxP3+ regulatory T cellsPloS oneJanuary 1, 2012Dolganiuc A, Kodys K, Marshall C, Saha B, Zhang S, Bala S, Szabo G.

(14) Adenoviruses-mediated transduction of human oesophageal carcinoma cells with the interferon-λ genes produced anti-tumour effectsBritish journal of cancerOctober 25, 2011Li Q, Kawamura K, Okamoto S, Fujie H, Numasaki M, Namba M, Nagata M, Shimada H, Kobayashi H, Tagawa M.

(15) Inhibition of dynamin-dependent endocytosis interferes with type III IFN expression in bacteria-infected human monocyte-derived DCsJournal of leukocyte biologyOctober 1, 2010Pietilä TE, Latvala S, Osterlund P, Julkunen I.

(16) Alpha/beta interferon (IFN-alpha/beta)-independent induction of IFN-lambda1 (interleukin-29) in response to Hantaan virus infectionJournal of virologySeptember 1, 2010Stoltz M, Klingström J.

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Human IL-28A/IFN-lambda 2 DuoSet ELISA

IL-28A/IFN-lambda 2 ELISA from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (16)

Reviews

IL-28A/IFN-lambda 2 ELISA from R&D Systems, a Bio-Techne Brand

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