Fig 1: GvHD-free, relapse-free survival (GRFS) and Overall survival associated serum proteins at Day-14. (A) Univariate (HR) and multivariate hazard ratios (adj. HR) with a 95% confidence interval (CI) based on the CoxPH model of GRFS. Regression coefficients are visualised as a forest plot (95% CI). (B) Correlation of relatively quantified Olink Normalised protein expression (NPX) data with absolute quantification of protein expression by ELISA in pg/ml for CCL23 (n=34). (C) Kaplan Meier curves of GRFS probability in patients stratified by high and low day 14 absolute CCL23 concentration. (D) Univariate and multivariate HR based on the CoxPH model of Overall Survival (OS). (E) Correlation of NPX with absolute quantification of protein expression by ELISA for PD-L1. (F) Kaplan Meier curves of OS probability in patients stratified by day 14 absolute PD-L1 concentration. CoxPH models adjusted for variables retained after LASSO selection. CCL23 and PD-L1 optimal concentration cutoff determined by maximally selected rank statistics.
Supplier Page from Abcam for Human CCL23 ELISA Kit