Arachidonic Acid-d8 from Cayman Chemical

Product Specs
ItemArachidonic Acid-d8
CompanyCayman Chemical
Price $461.00Supplier Page View Company Product Page
Catalog Number390010
Quantity5 mg
FormatA 10 mg/ml solution in methyl acetate
Research AreaFatty Acids, Lipid Biochemistry
Molecular Weight312.5
Purity≥99% deuterated forms (d1-d8)
Storage-20
FormulaC20H24D8O2
OriginUSA

Add to Compare List

Cayman Chemical

Cayman Chemical Company 1180 East Ellsworth Road

Ann Arbor, Michigan 48108

United States

Phone: (800) 364-9897
(734) 971-3640

Company Profile

Website: http://www.caymanchem.com/

(1) A multi-tiered workflow for examining organic acid profiles delineates tissue-specific changes in fatty acyl partitioning during agingCell Reports MethodsMay 18, 2026Zhiyang Zhou, Chenyin Cao, Taochao Lu, Yuyuan Ruan, Bowen Li, Mingjun Cao, Luyue Mo, Guanghou Shui, Sin Man Lamhydroxide (Sigma-Aldrich 05002), d31-FA-C16:0 (Sigma-Aldrich 366897), d8-FA-C20:4 (Cayman Chemicals 390010), butyric-2,2-d2-acid (CDN isotopes ND 0976), octanoic acid-1-13C (Sigma-Aldrich 296457), 2,2,3,3-d4-succinic

(2) Social isolation of aged mice drives dramatic release of inflammatory lipoxygenase-derived oxylipinsNPJ AgingMay 16, 2026Mareike Wichmann-Costaganna, Raphaëlle Petit, Julia Lindner, Madlen Haase, Vivien Bachmann, Robert Klaus Hofstetter, Markus Werner, Christiane Frahm, Oliver Werz, Patrick Schädeld5-RvD2 (Cayman Chemical; 11184), d4-PGE2 (Cayman Chemical; 10007273) and 10 μM d8-AA (Cayman Chemical; 390010). Finally, lysis buffer was added to yield a total volume of 3 mL and stored overnight at −20 °C to

(3) Methionine metabolism is linked with phospholipid and glutamine metabolism to drive ferroptosisCell ReportsApril 1, 2026Jong Woo Kim, Seo Young Jang, Yeon Jin Roh, Yeajin Ju, Ju-Bin Kang, Byung-Sun Park, Ji-Yoon Lee, Min Wook Kim, Byung Jun Jeong, Woosung Jung, et al.Stable isotope labeling was performed by feeding A549 and H1299 media supplemented with 2.5 μM AA-d8 (Cayman, 390010), 10% FBS, and 1% antibiotic-antimycin for 4 or 12 h to the cells. Then, the cells were washed with

(4) Palmitic acid induces UCP1-independent mitochondrial depolarization specifically in brown adipose tissueJournal of Biological ChemistryMarch 1, 2026Yuto Ishikawa, Isshin Shiiba, Eisho Kozakura, Haruto Yabu, Shun Hirose, Hijiri Oshio, Ken-ichi Yamada, Yuko Okamatsu-Ogura, Ryoko Inatome, Shigeru Yanagiresuspended in 300 μl of cold methanol containing 1 μM arachidonic acid-d8 (Cayman Chemical Company, 390010) and 100 μM butylated hydroxytoluene and then subjected to sonication for 10 s. After centrifugation

(5) 12-Hydroxyheptadecatrienoic Acid Predicts Hepatocellular Carcinoma Development During Nucleos(t)ide Analogue TherapyCancers (Basel)February 7, 2026Hiroko Ikenaga, Ritsuzo Kozuka, Kirara Inoue, Tsutomu Matsubara, Naoshi Odagiri, Kanako Yoshida, Kohei Kotani, Etsushi Kawamura, Atsushi Hagihara, Hideki Fujii, et al.leukotriene (LT) B4-d4 (Cayman Chemical; 320110), and 100 ng/mL arachidonic acid (AA)-d8 (Cayman Chemical; 390010). The mixture was then centrifuged at 15,000× g for 10 min to remove insoluble materials. The resulting

(6) Simvastatin overcomes the pPCK1‐pLDHA‐SPRINGlac axis‐mediated ferroptosis and chemo‐immunotherapy resistance in AKT‐hyperactivated intrahepatic cholangiocarcinomaCancer CommunicationsMay 29, 2025Jinghan Zhu, Yixiao Xiong, Yuxin Zhang, Huifang Liang, Kun Cheng, Yuanxiang Lu, Guangzhen Cai, Yang Wu, Yunhui Fan, Xiaoping Chen, et al.internal standards. Free fatty acids were quantified using d31‐16:0 (860393P, Sigma‐Aldrich) and d8‐20:4 (390010, Cayman Chemicals). 2.26 CoQ10H2/CoQ10 measurements by LC‐MS The method for CoQ10H2/CoQ10 measurements

(7) ATP Alters the Oxylipin Profiles in Astrocytes: Modulation by High Glucose and MetforminBrain SciMarch 11, 2025Alexey I. Drozhdev, Vladislav O. Gorbatenko, Sergey V. Goriainov, Dmitry V. Chistyakov, Marina G. Sergeeva12(S)-HETE-d8 (#334570), 15(S)-HETE-d8 (#334720), EPA-d5 (#10005056), DHA-d5 (#10005057), and ARA-d8 (#390010), from Cayman Chemical, Ann Arbor, MI, USA. For oxylipin analysis, lipid mediators were identified using

(8) Plasma endocannabinoidome and fecal microbiota interplay in people with HIV and subclinical coronary artery disease: Results from the Canadian HIV and Aging Cohort StudyiScienceAugust 16, 2024Ralph-Sydney Mboumba Bouassa, Giada Giorgini, Cristoforo Silvestri, Chanté Muller, Nayudu Nallabelli, Yulia Alexandrova, Madeleine Durand, Cécile Tremblay, Mohamed El-Far, Carl Chartrand-Lefebvre, et al.10011178 LEA-d4,Cayman Chemical,Cat# 9000553 DHEA-D4,Cayman Chemical,Cat# 9001108 AA-D8,Cayman Chemical,Cat# 390010 DHA-d5,Cayman Chemical,Cat# 10005057 ,, Critical commercial assays,Critical commercial assays,Critical

(9) Dietary fish oil enriched in very-long-chain polyunsaturated fatty acid reduces cardiometabolic risk factors and improves retinal functioniScienceDecember 15, 2023Zhi-Hong Yang, Aruna Gorusupudi, Todd A. Lydic, Anupam K. Mondal, Seizo Sato, Isao Yamazaki, Hideaki Yamaguchi, Jingrong Tang, Krishna Vamsi Rojulpote, Anna B. Lin, et al.(18:1/12:0),Avanti Polar Lipids,Cat# 860583 Deuterated (d8)-Arachidonic acid,Cayman Chemical,Cat# 390010 Triglyceride (14:1/14:1/14:1),NuCheck Prep,Cat# T-205 Liposome kit,Sigma-Aldrich,Cat# L4395-1VL Oil red O

(10) Aspirin eugenol ester ameliorates LPS-induced inflammatory responses in RAW264.7 cells and miceFrontiers in PharmacologyAugust 29, 2023Xu Liu, Qi Tao, Youming Shen, Xiwang Liu, Yajun Yang, Ning Ma, Jianyong Li(338410), 13-HODE-d4 (338610), 12-HETE-d8 (334570), 15-HETE-d8 (334720), DHA-d5 (10005057), AA-d8 (390010) were purchased from Cayman Chemical Co., (Ann Arbor, MI, United States). 2.2 Animal experiment and

(11) Multi-Omics Approach Points to the Importance of Oxylipins Metabolism in Early-Stage Breast CancerCancers (Basel)April 18, 2022Dmitry V. Chistyakov et al.oleoyl ethanolamide-d4 (cat. no. 9000552), EPA-d5 (cat. no. 10005056), DHA-d5 (cat. no. 10005057), and AA-d8 (cat. no. 390010) (Cayman Chemical, Ann Arbor, MI, USA). An Oasis® PRIME hydrophilic-lipophilic balance (HLB) solid-phase

(12) Raman microscopy-based quantification of the physical properties of intracellular lipidsCommunications BiologyDecember 1, 2021Masaaki Uematsu, Takao Shimizu(16497), C18:1(d17) (9000432), C18:2(d4) (390150), C18:2(d11) (9002193), C18:3(d14) (9000433), C20:4(d8) (390010), C20:4(d11) (10006758), C20:5(d5) (10005056), C22:6(d5) (10005057), C16:0(d0) (10006627), C18:1(d0)

(13) Proteomic and lipidomic profiling of demyelinating lesions identifies fatty acids as modulators in lesion recoveryCell ReportsOctober 26, 2021Horst Penkert et al.11184), d4-prostaglandin E2 (Cayman Chemical; 10007273) and 10 μM d8-arachidonic acid (Cayman Chemical; 390010). In brief, samples were kept at −20°C for 60 min to allow protein precipitation. After centrifugation

(14) Super-multiplex imaging of cellular dynamics and heterogeneity by integrated stimulated Raman and fluorescence microscopyiScienceAugust 20, 2021Jingwen Shou, Robert Oda, Fanghao Hu, Keiko Karasawa, Mutsuo Nuriya, Masato Yasui, Bruce Shiramizu, Wei Min, Yasuyuki Ozekiproteins" ,, Oleic acid,Wako Pure Chemical Industries,155-03401 Arachidonic acid-d8,Cayman Chemical,390010 Palmitic acid-d31,Wako Pure Chemical Industries,16497 Carbow Mito,"Hu et al., 2018",N/A Carbow Lyso,"Hu

(15) Modulation of the Primary Astrocyte-Enriched Cultures' Oxylipin Profiles Reduces NeurotoxicityMetabolitesJuly 30, 2021Guryleva MV, Chistyakov DV, Lopachev AV, Goriainov SV, Astakhova AA, Timoshina YA, Khutorova AV, Fedorova TN, Sergeeva MG.15(S)-HETE-d8 (cat.no. 334720), EPA-d5 (cat.no, 10005056), DHA-d5 (cat.no. 10005057), and AA-d8 (cat. No. 390010) were from Cayman Chemical, Ann Arbor, MI, USA. Oasis® PRIME HLB cartridges (60 mg, 3cc, cat.no. 186008056)

(16) Global profiling of gut microbiota-associated lipid metabolites in antibiotic-treated mice by LC-MS/MS-based analysesSTAR ProtocolsJune 1, 2021Nobuyuki Okahashi, Masahiro Ueda, Shu Yasuda, Hiroshi Tsugawa, Makoto AritaLeukotriene D4-d5,Cayman,10006199 15-Hydroxyeicosatetraenoic acid-d8,Cayman,334720 Arachidonic acid-d8,Cayman,390010 "14, 15-Epoxy-5, 8, 11-eicosatrienoic acid-d11",Cayman,10006410 Prostaglandin B2-d4,Cayman,311210 8-iso Prostaglandin F2α-d4

(17) High Glucose Shifts the Oxylipin Profiles in the Astrocytes towards Pro-Inflammatory StatesMetabolitesMay 13, 2021Dmitry V. Chistyakov, Sergei V. Goriainov, Alina A. Astakhova, Marina G. Sergeeva15(S)HETE-d8 (cat.no. 334720), EPA-d5 (cat.no, 10005056), DHA-d5 (cat.no. 10005057), AA-d8 (cat. No. 390010) and were from Cayman Chemical, Ann Arbor, MI, USA. Oasis® PRIME HLB cartridges (60 mg, 3cc, cat.no.

(18) Profiling of MicroRNA Targets Using Activity-Based Protein Profiling: Linking Enzyme Activity to MicroRNA-185 FunctionCell chemical biologyFebruary 18, 2021Filip R, Desrochers GF, Lefebvre DM, Reed A, Singaravelu R, Cravatt BF, Pezacki JP.Benjamin Cravatt, Scripps Research Institute(Niphakis et al., 2013)",N/A Arachidonic acid-d8,Cayman,Cat# 390010-1 2-AG-d5,Cayman,Cat# 362162 Critical Commercial Assays,Critical Commercial Assays,Critical Commercial

(19) Polyunsaturated fatty acid biosynthesis pathway determines ferroptosis sensitivity in gastric cancerProceedings of the National Academy of Sciences of the United States of AmericaDecember 22, 2020Lee JY, Nam M, Son HY, Hyun K, Jang SY, Kim JW, Kim MW, Jung Y, Jang E, Yoon SJ, et al.obtained from Molecular Probes and dissolved in dimethyl sulfoxide (DMSO). LA (90150), AA (90010), and AA-d8 (390010) were purchased from Cayman Chemical. All chemicals were stored at −20 °C, except CP-24879, which was stored

(20) Oxylipin Profiles in Plasma of Patients with Wilson’s DiseaseMetabolitesMay 29, 2020Nadezhda V. Azbukina, Alexander V. Lopachev, Dmitry V. Chistyakov, Sergei V. Goriainov, Alina A. Astakhova, Vsevolod V. Poleshuk, Rogneda B. Kazanskaya, Tatiana N. Fedorova, Marina G. Sergeevaoleoyl ethanolamide-d4 (cat.no. 9000552), EPA-d5 (cat.no, 10005056), DHA-d5 (cat.no. 10005057), and AA-d8 (cat. No. 390010) (Cayman Chemical, Ann Arbor, MI, USA). An Oasis® PRIME HLB solid-phase lipid extraction cartridge (60

Be the First to Write a Review!