Anti-Ganglioside GD3 antibody [R24] ab11779 from Abcam

Product Specs
ItemAnti-Ganglioside GD3 antibody [R24]
CompanyAbcam
Price $419.00Supplier Page View Company Product Page
Catalog Numberab11779
IsotypeIgG3
HostMouse
CloneR24
ApplicationsICC/IF, IHC-Fr, IHC-P
Quantity500 µL
ClonalityMonoclonal
Conjugate/TagUnconjugated
FormatAffinity purified from tissue culture supernatant
Concentration0.4 mg/ml
ReactivityHuman
Antibody TypePrimary Antibody
Research AreaImmuno-oncology
TargetGanglioside GD3

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Abcam

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Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

Company Profile

Website: http://www.abcam.com

(1) Gene Therapy Targeting GD3 Synthase Protects Against MPTP‐Induced Parkinsonism and Executive DysfunctionEuropean Journal of NeuroscienceFebruary 13, 2026Panchanan Maiti, Yi Xue, Tonia S. Rex, Michael P. McDonaldMillipore), GM1 (2.0 μg/ml; GM1–1, Developmental Studies Hybridoma Bank, Iowa City, IA), or GD3 (0.8 μg/ml; #ab11779, Abcam) in 3–6 mice per group. Following incubation TH- and GD3-stained sections were rinsed three times

(2) The GD3 ganglioside promotes cell growth, plasticity and chemotherapy resistance of human glioblastoma cancer stem cellsCancer Cell IntJuly 2, 2025Victoria Hein, Nathalie Baeza-Kallee, Raphaël Bergès, Nora Essakhi, Aurélie Soubéran, Carole Colin, Philippe Morando, Romain Appay, Thomas Graillon, Aurélie Tchoghandjian, et al.through 40 μm, centrifugated and incubated with anti-GD3 mouse monoclonal IgG3 antibody (R24 clone, 1/5, ab11779, Abcam) for 20 min at 4 °C, washed and incubated with magnetic microbead-tagged mouse-specific IgG rat

(3) A ganglioside-based immune checkpoint enables senescent cells to evade immunosurveillance during agingNature AgingDecember 27, 2024Charlène Iltis, Iryna Moskalevska, Antoine Debiesse, Laetitia Seguin, Christina Fissoun, Ludovic Cervera, Lyvia Moudombi, Maude Ardin, Anthony Ferrari, Coline Eliott, et al.Vector Laboratories, BMK-2202 and SP-2001) and incubated overnight at 4 °C with mouse monoclonal anti-GD3 (Abcam, ab11779; 1:40), anti-p16 (Abcam, ab54210; 1:100) or rabbit anti-p21 (Abcam, ab188224; 1:100). Primary antibody

(4) Autophagy Promotes Enrichment of Raft Components within Extracellular Vesicles Secreted by Human 2FTGH CellsInternational Journal of Molecular SciencesJune 4, 2024Valeria Manganelli, Luciana Dini, Stefano Tacconi, Simone Dinarelli, Antonella Capozzi, Gloria Riitano, Serena Recalchi, Tuba Rana Caglar, Federica Fratini, Roberta Misasi, et al.anti-LC3B-II (Novus Biologicals, NB600-1384SS) and 10 μg/mL of anti-ganglioside GD3 (Abcam, Cambridge, UK, ab11779). Colloidal gold-conjugated goat anti-rabbit IgG H&L (Abcam, 6 nm, ab41498) and protein A Gold Conjugate

(5) GD2 and GD3 gangliosides as diagnostic biomarkers for all stages and subtypes of epithelial ovarian cancerFrontiers in oncologyJanuary 1, 2023Galan A, Papaluca A, Nejatie A, Matanes E, Brahimi F, Tong W, Hachim IY, Yasmeen A, Carmona E, Klein KO, et al.14G2a (BD Pharmingen, Cat. 554272, used at 1:400 or 1:1200 depending on lot), anti-GD3 R24 (Abcam, Cat. ab11779, used at 1:400 or 1:200 depending on lot), and anti-human HE4/WFDC2 antibody (R&D systems, MAB6274,

(6) Ganglioside GD3 is up-regulated in microglia and regulates phagocytosis following global cerebral ischemiaJournal of neurochemistryAugust 1, 2021Wang J, Zhang Q, Lu Y, Dong Y, Dhandapani KM, Brann DW, Yu RK.exposure for each marker in all analyzed sections. DAB stains for anti-GD3 (R24, mouse, 1:200, Abcam, Cat. ab11779) and anti-S100β (mouse, 1:400, Sigma, Cat. S2523) were conducted as previously described (Wang et al.

(7) Gangliosides are essential endosomal receptors for quasi-enveloped and naked hepatitis A virusNature microbiologySeptember 1, 2020Das A, Barrientos R, Shiota T, Madigan V, Misumi I, McKnight KL, Sun L, Li Z, Meganck RM, Li Y, et al.anti-β-Actin (clone AC-74, catalog# A2228) were from Millipore Sigma, and anti-GD3 from Abcam (clone R24, #ab11779). Species-specific Alexa-fluor conjugated secondary antibodies were purchased from Thermo Fisher Scientific.

(8) Upregulation of cell surface GD3 ganglioside phenotype is associated with human melanoma brain metastasisMolecular oncologyAugust 1, 2020Ramos RI, Bustos MA, Wu J, Jones P, Chang SC, Kiyohara E, Tran K, Zhang X, Stern SL, Izraely S, et al.CA, USA, Cat# 563439); unconjugated mouse mAb anti‐GD3 (Clone R24, Abcam, Cambridge, MA, USA, Cat# ab11779) with secondary polyclonal Ab goat anti‐mouse IgG3‐APC‐Cy7 (Abcam Cat# ab47000); and purified human

(9) Sialylation of Human Natural Killer (NK) Cells Is Regulated by IL-2Journal of Clinical MedicineJune 11, 2020Philip Rosenstock, Kaya Bork, Chiara Massa, Philipp Selke, Barbara Seliger, Rüdiger Horstkortecells J. Clin. Med. 2020, 9, 1816 4 of 12 per tube were stained with monoclonal anti-GD3 antibody (ab11779, Abcam, Cambridge, UK) at 1:50 dilution or with biotinylated Sambucus Nigra Lectin (SNA, 20 µg/mL) or

(10) Caveolin-1 Promotes Early Neuronal Maturation via Caveolae-Independent Trafficking of N-Cadherin and L1iScienceSeptember 28, 2018Shikanai M, Nishimura YV, Sakurai M, Nabeshima YI, Yuzaki M, Kawauchi T.

(11) Cerebral organoids derived from Sandhoff disease-induced pluripotent stem cells exhibit impaired neurodifferentiationJournal of lipid researchMarch 1, 2018Allende ML, Cook EK, Larman BC, Nugent A, Brady JM, Golebiowski D, Sena-Esteves M, Tifft CJ, Proia RL.A2576; TCI, Tokyo, Japan) (20); anti-ganglioside GD3, clone R24 (mouse monoclonal IgG3, catalog number ab11779; Abcam, Cambridge, MA); anti-galactosylceramide, clone mGalC (mouse monoclonal IgG3, catalog number

(12) High-Affinity GD2-Specific CAR T Cells Induce Fatal Encephalitis in a Preclinical Neuroblastoma ModelCancer immunology researchJanuary 1, 2018Richman SA, Nunez-Cruz S, Moghimi B, Li LZ, Gershenson ZT, Mourelatos Z, Barrett DM, Grupp SA, Milone MC.incubated with anti-GD2-PE, clone 14G2a (BioLegend, cat no. 357304), purified anti-GD3 (Abcam, cat. no AB11779), or respective isotype controls at 1:30 dilution for 15 minutes at room temperature. For the anti-GD3

(13) Interaction of glycosphingolipids GD3 and GD2 with growth factor receptors maintains breast cancer stem cell phenotypeOncotargetJuly 18, 2017Liang YJ, Wang CY, Wang IA, Chen YW, Li LT, Lin CY, Ho MY, Chou TL, Wang YH, Chiou SP, et al.

(14) Evidence for the involvement of lipid rafts localized at the ER-mitochondria associated membranes in autophagosome formationAutophagyJune 2, 2016Garofalo T, Matarrese P, Manganelli V, Marconi M, Tinari A, Gambardella L, Faggioni A, Misasi R, Sorice M, Malorni W.

(15) Molecular subtyping of metastatic melanoma based on cell ganglioside metabolism profilesBMC CancerAugust 1, 2014Cristina Tringali, Ilaria Silvestri, Francesca Testa, Paola Baldassari, Luigi Anastasia, Roberta Mortarini, Andrea Anichini, Alejandro López-Requena, Guido Tettamanti, Bruno Venerando

(16) Mice lacking GD3 synthase display morphological abnormalities in the sciatic nerve and neuronal disturbances during peripheral nerve regenerationPloS oneJanuary 1, 2014Ribeiro-Resende VT, Araújo Gomes T, de Lima S, Nascimento-Lima M, Bargas-Rega M, Santiago MF, Reis RA, de Mello FG.double immunolabeled for integrin-β1 (Abcam, Cat# ab52971, RRID: AB_870695) and either GD3 (Abcam, Cat# ab11779, RRID: AB_298562) or 9-O-acetyl GD3 (CD-60b) (Santa Cruz Biotechnology, Cat# sc-32269, RRID: AB_627135). Semi-thin

(17) Differential expression profiles of glycosphingolipids in human breast cancer stem cells vs. cancer non-stem cellsProceedings of the National Academy of SciencesMarch 26, 2013Yuh-Jin Liang, Yao Ding, Steven B. Levery, Marlin Lobaton, Kazuko Handa, Sen-itiroh Hakomori

(18) The ganglioside G(D2) induces the constitutive activation of c-Met in MDA-MB-231 breast cancer cells expressing the G(D3) synthaseGlycobiologyJune 1, 2012Aurélie Cazet, Marie Bobowski, Yoann Rombouts, Jonathan Lefebvre, Agata Steenackers, Iuliana Popa, Yann Guérardel, Xuefen Le Bourhis, David Tulasne, Philippe Delannoy

(19) A Prominin-1-Rich Pediatric Glioblastoma: Biologic Behavior Is Determined by Oxygen Tension-Modulated CD133 Expression but Not Accompanied by Underlying Molecular ProfilesTranslational oncologyJune 1, 2012Donovan LK, Potter NE, Warr T, Pilkington GJ.

(20) Mechanism of abnormal growth in astrocytes derived from a mouse model of GM2 gangliosidosisJournal of neurochemistryNovember 1, 2009Nagako Kawashima, Daisuke Tsuji, Tetsuya Okuda, Kohji Itoh, Ken-ichi Nakayama

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Anti-Ganglioside GD3 antibody [R24] from Abcam

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Anti-Ganglioside GD3 antibody [R24] from Abcam

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