CD99 / MIC2 (Ewings Sarcoma Marker) MBS439402 from MyBioSource.com

Product Specs
ItemCD99 / MIC2 (Ewings Sarcoma Marker)
CompanyMyBioSource.com
Price $275.00Supplier Page View Company Product Page
Catalog NumberMBS439402
Quantity0.5 mL
ApplicationsFlow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin
ConcentrationCulture Supernatant
Conjugate/TagUnconjugated
FormatTissue culture supernatant with 0.05% Azide. Contact us if you require it in a different format
ReactivityHuman
TargetCD99 / MIC2
IsotypeIgG1 kappa
Molecular WeightAntigen: 27-32kDa
Clone12E7
HostMouse
ImmunogenRecognizes a sialoglycoprotein of 27-32kDa, identified as CD99, or MIC2 gene product, or E2 antigen. MIC2 gene is located in the pseudo-autosomal region of the human X and Y chromosome. MIC2 gene encodes two distinct proteins, which are produced by alternative splicing of the CD99 gene transcript and are identified as bands of 30 and 32kDa (p30/32). Although its function is not fully understood, CD99 is implicated in various cellular processes including homotypic aggregation of T cells, upregulation of T cell receptor and MHS molecules, apoptosis of immature thymocytes and leukocyte diapedesis. CD99 is expressed on the cell membrane of some lymphocytes, cortical thymocytes, and granulosa cells of the ovary. Most pancreatic islet cells, Sertoli cells of the testis, and some endothelial cells express this antigen. Mature granulocytes express very little or no CD99. MIC2 is strongly expressed on Ewing's sarcoma cells and primitive peripheral neuroectodermal tumors
NCBI Full Gene NameCD99 molecule
NCBI Gene AliasesHBA71, MIC2Y, MSK5X, MIC2X, MIC2
ClonalityMonoclonal