MyBioSource.com's GPR183 Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA. The GPR183 Antibody was generated using GPR183 as the antigen and it reacts with Human.
Description
Receptor for oxysterol 7-alpha,25-dihydroxycholesterol (7-alpha,25-OHC) and other related oxysterols. Binding of 7-alpha,25-OHC mediates the correct localization of B-cells during humoral immune responses. Promotes activated B-cell localization in the outer follicle and interfollicular regions. Its specific expression during B-cell maturation helps position B-cells appropriately for mounting T-dependent antibody responses. Signals constitutively through G(i)-alpha, but not through G(s)-alpha or G(q)-alpha. Signals constitutively also via MAPK1/3 (ERK1/2)