CD18 / Integrin beta-2 (ITGB2) MBS439122 from MyBioSource.com

Product Specs
ItemCD18 / Integrin beta-2 (ITGB2)
CompanyMyBioSource.com
Price $275.00Supplier Page View Company Product Page
Catalog NumberMBS439122
Quantity0.1 mg
ApplicationsFunctional Studies, Flow Cytometry (FC/FACS), Immunofluorescence (IF)
ConcentrationPurified Ab with BSA and Azide at 200ug/ml
Conjugate/TagUnconjugated
Format200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml
ReactivityHuman
TargetCD18
IsotypeIgG2a kappa
Molecular WeightAntigen: 95kDa
Clone68-5A5
HostMouse
ImmunogenIt recognizes a transmembrane glycoprotein of 95kDa, identified as CD18 or integrin -2. It complexes non-covalently with either L, M, or X integrin (CD11a, b, or c) to form the heterodimers, LFA-1, Mac-1, and p150,95, respectively. LFA-1 is the receptor for three members of the Ig supergene family of proteins, ICAM-1 (CD54), ICAM-2 (CD102), and Mac-1 and p150,95 bind to ICAM-1, fibrinogen, and iC3b. ICAM-3 (CD50). CD18/CD11 heterodimeric molecules are involved with cell/cell and cell/extracellular adhesion in immune and inflammatory responses. This MAb blocks these cellular interactions
NCBI Full Gene Nameintegrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
NCBI Gene AliasesMF17, LAD, MFI7, MAC-1, LCAMB, LFA-1, CD18
ClonalityMonoclonal