The APAF1 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to APAF1. This antibody recognizes Human antigen. The APAF1 Antibody has been shown to work in the following applications: ELISA, and Immunohistochemistry.
Description
Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis