The SF3B3 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to SF3B3, and splicing factor 3b subunit 3. This antibody recognizes Human antigen. The SF3B3 Antibody has been shown to work in the following applications: ELISA, and Immunohistochemistry.
Description
Subunit of the splicing factor SF3B required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron