IL-18 R alpha/IL-1 R5 Antibody MAB12161-100 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemIL-18 R alpha/IL-1 R5 Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $479.00Supplier Page View Company Product Page
Catalog NumberMAB12161-100
Quantity100 ug (also 25 ug, 500 ug)
ApplicationsImmunoprecipitation,Western Blot,Neutralization
Conjugate/TagUnconjugated
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
ReactivityMouse
TargetIL-18 R alpha/IL-1 R5
IsotypeIgG2a
Clone112624
HostRat
ImmunogenMouse myeloma cell line NS0-derived recombinant mouse IL-18 R alpha, Ser19-Gly326, Accession # Q61098
NCBI Full Gene Nameinterleukin 18 receptor 1
NCBI Gene AliasesIL-18Ralpha, CDw218a, IL-1Rrp, CD218a, IL-18R-alpha, Il1rrp, IL18Ralpha2, Il18ralpha, IL18RA, IL1RRP
ClonalityMonoclonal
ConcentrationLYOPH
PurityProtein A or G purified from hybridoma culture supernatant
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: Detects mouse IL-18 R in direct ELISAs. In direct ELISAs, this antibody does not cross-react with recombinant mouse (rm) IL-1 RI, rmIL-1 RII, rhIL-1 R3, recombinant human (rh) IL-1 R4, rhIL-1 R5, recombinant rat IL-1 R6, rmIL-1 R7, rhIL-1 R8, rhIL-1 R9, or rmSIGIRR.

Sizes Available: 100 ug (also 25 ug, 500 ug)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Innate acting memory Th1 cells modulate heterologous diseasesProceedings of the National Academy of Sciences of the United States of AmericaJune 11, 2024Rakebrandt N, Yassini N, Kolz A, Schorer M, Lambert K, Goljat E, Estrada Brull A, Rauld C, Balazs Z, Krauthammer M, et al.

(2) Treatment of mice with S4B6 IL-2 complex prevents lethal toxoplasmosis via IL-12- and IL-18-dependent interferon-gamma production by non-CD4 immune cellsScientific reportsAugust 4, 2020Kupz A, Pai S, Giacomin PR, Whan JA, Walker RA, Hammoudi PM, Smith NC, Miller CM.

(3) Protective effect of neutralizing anti-IL-18α monoclonal antibody on a mouse model of acute graft-versus-host diseaseOncology reportsOctober 1, 2015Li X, Zhang C, Chen W, Pan B, Kong F, Zheng K, Tang R, Zeng L.

(4) Interleukin 18 function in atherosclerosis is mediated by the interleukin 18 receptor and the Na-Cl co-transporterNature medicineJuly 1, 2015Wang J, Sun C, Gerdes N, Liu C, Liao M, Liu J, Shi MA, He A, Zhou Y, Sukhova GK, et al.

(5) The interaction between IL-18 and IL-18 receptor limits the magnitude of protective immunity and enhances pathogenic responses following infection with intracellular bacteriaJournal of immunology (Baltimore, Md. : 1950)August 1, 2011Ghose P, Ali AQ, Fang R, Forbes D, Ballard B, Ismail N.

(6) Protection of CD8+ T cells from activation-induced cell death by IL-18Journal of leukocyte biologyJuly 1, 2007Li W, Kashiwamura S, Ueda H, Sekiyama A, Okamura H.

(7) IL-18 is induced and IL-18 receptor alpha plays a critical role in the pathogenesis of cigarette smoke-induced pulmonary emphysema and inflammationJournal of immunology (Baltimore, Md. : 1950)February 1, 2007Kang MJ, Homer RJ, Gallo A, Lee CG, Crothers KA, Cho SJ, Rochester C, Cain H, Chupp G, Yoon HJ, et al.

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IL-18 R alpha/IL-1 R5 Antibody

IL-18 R alpha/IL-1 R5 Antibody

IL-18 R alpha/IL-1 R5 Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (7)

Reviews

IL-18 R alpha/IL-1 R5 Antibody from R&D Systems, a Bio-Techne Brand

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